Cyclization Reactions for Synthesis of Benzthiazole- A Review

Authors

  • Praul Singh Advance Institute of Biotech and Paramedical Sciences, Naramau, Kanpur.
  • Ashish Srivastava Pranveer Singh Institute of Technology, Bhauti, Kanpur.
  • Abhinav Prasoon Mishra Pranveer Singh Institute of Technology, Bhauti, Kanpur.
  • Reena Mehtab Pranveer Singh Institute of Technology, Bhauti, Kanpur.

Keywords:

Benzothiazole, Cyclization, Catalysts

Abstract

Benzoheterocycles such as benzothiazoles can serve as unique and versatile scaffolds for experimental drug design. Among the all benzoheterocycles, benzothiazole has considerable place in research area especially in synthetic as well as in pharmaceutical chemistry because of its potent and significant pharmacological activities. Various benzothiazoles such as 2-aryl benzothiazole received much attention due to unique structure. Development of combination of 2- aminobenzothiazoles with other heterocyclic is a well known approach to design new drug like molecules, which allows achieving new pharmacological profile, action, toxicity lowering. In this review, we discussed various methods to synthesize as well as cyclization of benzothiazole derivatives and various structural alterations conducted on benzothiazole ring and preferential specificities imparted in their biological responses.

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Published

2018-10-26

How to Cite

Singh, P., Srivastava, A., Mishra, A. P., & Mehtab, R. (2018). Cyclization Reactions for Synthesis of Benzthiazole- A Review. Journal of Drug Discovery and Development ( ISSN:2581-6861), 1(1), 4-12. Retrieved from https://medicaljournalshouse.com/index.php/JDrug-Discovery-Development/article/view/48

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Vol. 1 No. 1 (2017): Journal of Drug Discovery and Development

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