Medicinal Properties of Antioxidant Pomegranate in Cardiovascular Health
Keywords:
Pomegranate, Phytochemicals, Antioxidant, Cardiovascular, Cholesterol, HDL, LDL, Antihypertensive, Antiatherogenic, TriglyceridesAbstract
Pomegranate is a plant that contains in its fruit, juice, peel, seeds,
flowers, bark and roots high concentration of several phytochemicals
as polyphenols, tannins, ellagitannins, gallotannins, flavanols, flavones,
flavanones, pro-anthocyanidins, anthocyanins, organic acids, alkaloids
and others. Most of these compounds possess strong antioxidant
properties. Research has shown that due to this antioxidant activity,
pomegranate phytochemicals as mixture in the juice, in the plantpart
extracts and as isolated compounds may offer many benefits
to cardiovascular health. The oxidation of Low-Density Lipoprotein
(LDL) is the main cause of heart diseases. Pomegranate improves
the antioxidant status and decreases the oxidative stress. It reduces
serum total cholesterol, triglycerides, LDL levels, increases High
Density Lipoprotein (HDL), protects against atherosclerosis and acts
as antihypertensive. It is found to increase the activity of paraoxonase-1
and paraoxonase-2, serum and tissue enzyme respectively that protect
against atherosclerosis. Besides it reduces cardiac fibrosis in diabetic
patients, improves the cardiovascular health of aged people and reduces
body weight. It is reversing the biochemical changes due to diabetes
and the proatherogenic effects due to perturbed shear stress. It is found
to affect the values of biochemical parameters as total cholesterol,
triglycerides, LDL, HDL only when they are not normal showing a
tendency to the normal, healthy condition than simply changing values
even towards the desired direction. In the safety tests that were carried
out no side effects were observed.
How to cite this article:
Stefanou V, Papatheodorou S, Vougiouklaki D,
Antonopoulos D, Lougovois V, Tsaknis I et al.
Medicinal Properties of Antioxidant Pomegranate
in Cardiovascular Health. Int J Preven Cardio
2020; 1(1): 1-10.
Downloads
Published
Issue
Section
License
Copyright (c) 2020 International Journal of Preventive Cardiology

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
We, the undersigned, give an undertaking to the following effect with regard to our article entitled
“_______________________________________________________________________________________________________________________________________________________________________________
________________________________________________________________________________” submitted for publication in (Journal title)________________________________________________ _______________________________________________________Vol.________, Year _________:-
1. The article mentioned above has not been published or submitted to or accepted for publication in any form, in any other journal.
2. We also vouchsafe that the authorship of this article will not be contested by anyone whose name(s) is/are not listed by us here.
3. I/We declare that I/We contributed significantly towards the research study i.e., (a) conception, design and/or analysis and interpretation of data and to (b) drafting the article or revising it critically for important intellectual content and on (c) final approval of the version to be published.
4. I/We hereby acknowledge ADRs conflict of interest policy requirement to scrupulously avoid direct and indirect conflicts of interest and, accordingly, hereby agree to promptly inform the editor or editor's designee of any business, commercial, or other proprietary support, relationships, or interests that I/We may have which relate directly or indirectly to the subject of the work.
5. I/We also agree to the authorship of the article in the following sequence:-
Authors' Names (in sequence) Signature of Authors
1. _____________________________________ _____________________________________
2. _____________________________________ _____________________________________
3. _____________________________________ _____________________________________
4. _____________________________________ _____________________________________
5. _____________________________________ _____________________________________
6. _____________________________________ _____________________________________
7. _____________________________________ _____________________________________
8. _____________________________________ _____________________________________
Important
(I). All the authors are required to sign independently in this form in the sequence given above. In case an author has left the institution/ country and whose whereabouts are not known, the senior author may sign on his/ her behalf taking the responsibility.
(ii). No addition/ deletion/ or any change in the sequence of the authorship will be permissible at a later stage, without valid reasons and permission of the Editor.
(iii). If the authorship is contested at any stage, the article will be either returned or will not be
processed for publication till the issue is solved.