Synergistic Effect of Racecadotril and Loperamide by Gastrointestinal Motility Test

Authors

  • Imadulla Baig Department of Pharmacology, National College of Pharmacy, Shivamogga, Karnataka, India.
  • Veerashekar T Department of Pharmacology, National College of Pharmacy, Shivamogga, Karnataka, India.
  • Shekshavali T Department of Pharmacology, National College of Pharmacy, Shivamogga, Karnataka, India.
  • Nagaraja HR Department of Pharmacology, National College of Pharmacy, Shivamogga, Karnataka, India.
  • Ruchitha V Department of Pharmacology, National College of Pharmacy, Shivamogga, Karnataka, India.

Abstract

The purpose of the study is to implicit spectacular effects of drug synergism, when two similarly mimicking drugs are administered concomitantly the effects are satisfying for the therapeutic effect expected. In this study two market available drugs Racecadotril and Loperamide were used in albino rat using Gastrointestinal Motility test as antidiarrheal screening model for studying the effects of these two drugs against diarrhoea synergistically. The results were quite satisfactorily achieved as per anticipation, further models can be used to confirm the same and also this might be the prerequisite for further development of a formulation in future.

How to cite this article:
Baig I, Veerashekar T, Shekshavali T et al. Synergistic Effect of Racecadotril and Loperamide by Gastrointestinal Motility Test. J Adv Res Biochem Pharma 2021; 4(2): 7-10.

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Published

2022-04-13