Seroprevalence of COVID-19 Antibody among Health Care Workers in the Remote Andaman & Nicobar Islands, India
Abstract
Introduction: Health Care Workers (HCW) are the frontline workforce and highly exposed to COVID-19 infection. There is no baseline line data available about seroprevalence of SARS-CoV-2 antibodies among different categories of HCWs in the isolated Andaman & Nicobar Island. Hence,a serosurvey was carried out to find out the type and mode of COVID-19 spread through estimation of SARS-CoV2 antibodies among health care workers across South Andaman district. Materials and Methods: A cross sectional study was conducted among the health care workers. A total of 1659 HCWs were selected randomly across all the categories of HCWs working in the island. Their venous blood samples were tested for COVID-19 IgG antibodies by using Erba Lisa ELISA-based kit.
Results: The overall seroprevalence was found to be 40.2 %. The highest prevalence was seen among health associate professionals (45.6%) followed by health support and management personnel (37.6%) & Health Professionals (32.6%) respectively.
Conclusion: From the present studywe draw an inference that SARS -CoV-2 IgG antibodies were comparatively higher among health care workers in South Andaman than other parts of the country. A large section of health care workers across South Andaman district are yet to develop antibodies and at higher risk of contracting COVID-19 infection.
How to cite this article:
Burma A, Kumar D, Mandal AK. Seroprevalence of COVID-19 Antibody among Health Care Workers in the Remote Andaman & Nicobar Islands, India. Rec Adv Path Lab Med. 2020;6(3&4):10-16.
DOI: https://doi.org/10.24321/2454.8642.202005
References
Goenka M, Afzalpurkar S, Goenka U, Das SS, Mukherjee M, Jajodia S, Shah BB, Patil VU, Rodge G, Khan U, Bandyopadhyay S. Seroprevalence of COVID-19 amongst health care workers in a tertiary care hospital of a metropolitan city from India. J Assoc Physicians India. 2020 Nov;68(11):14-9. [PubMed] [Google Scholar]
Siddiqui S, Naushin S, Pradhan S, Misra A, Tyagi A, Loomba M, Waghdhare S, Pandey R, Sengupta S, Jha S. SARS-CoV-2 antibody seroprevalence and stability in a tertiary care hospital-setting. MedRxiv. 2020 Jan 1. [Google Scholar]
Singhal T, Shah S, Naik R, Kazi A, Thakkar P. Prevalence of COVID-19 antibodies in healthcare workers at the peak of the pandemic in Mumbai, India: A preliminary study. Indian J Med Microbiol. 2020 Jul-Dec;38(3& 4):461–3. [PubMed] [Google Scholar]
Who. int. Accessed July 21, 2021. Available from: https://www.who.int/hrh/statistics/Health_workers_classification.pdf.
Dave M, Vijayvargiya R, Poswal L, Bedi V, Sharma, Deval N.Study of COVID 19 seroprevalence among health care workers at dedicated COVID hospital in Southern Rajasthan. Indian J Clin Prac.2020;31(2):107-11.
Murhekar MV, Bhatnagar T, Thangaraj JWV, Saravanakumar V, Kumar MS, Selvaraju S, Rade K, Kumar CPG, Sabarinathan R, Turuk A, Asthana S, Balachandar R, Bangar SD, Bansal AK, Chopra V, Das D, Deb AK, Devi KR, Dhikav V, Dwivedi GR, Khan SMS, Kumar MS, Laxmaiah A, Madhukar M, Mahapatra A, Rangaraju C, Turuk J, Yadav R, Andhalkar R, Arunraj K, Bharadwaj DK, Bharti P, Bhattacharya D, Bhat J, Chahal AS, Chakraborty D, Chaudhury A, Deval H, Dhatrak S, Dayal R, Elantamilan D, Giridharan P, Haq I, Hudda RK, Jagjeevan B, Kalliath A, Kanungo S, Krishnan NN, Kshatri JS, Kumar A, Kumar N, Kumar VGV, Lakshmi GGJN, Mehta G, Mishra NK, Mitra A, Nagbhushanam K, Nimmathota A, Nirmala AR, Pandey AK, Prasad GV, Qurieshi MA, Reddy SD, Robinson A, Sahay S, Saxena R, Sekar K, Shukla VK, Singh HB, Singh PK, Singh P, Singh R, Srinivasan N, Varma DS, Viramgami A, Wilson VC, Yadav S, Yadav S, Zaman K, Chakrabarti A, Das A, Dhaliwal RS, Dutta S, Kant R, Khan AM, Narain K, Narasimhaiah S, Padmapriyadarshini C, Pandey K, Pati S, Patil S, Rajkumar H, Ramarao T, Sharma YK, Singh S, Panda S, Reddy DCS, Bhargava B; ICMR Serosurveillance Group.SARS-CoV-2 seroprevalence among the general population and healthcare workers in India, December 2020-January 2021. Int J Infect Dis. 2021 Jul;108:145-55. [PubMed] [Google Scholar]
Andaman UT Administration. Gov.in. Accessed July 26, 2021. Available from: https://www.andamantourism.gov.in/about.php.
Woon YL, Lee YL, Chong YM, Ayub NA, Krishnabahawan SL, Lau JFW, Subramaniam-Kalianan R, Sam IC, Chan YF, Sevalingam RK, Ramli A, Chuah CH, Mat-Hussin H, Leong CL, Chidambaram SK, Peariasamy KM, Goh PP. Serology surveillance of SARS-CoV-2 antibodies among healthcare workers in COVID-19 designated facilities in Malaysia. Lancet Reg Health West Pac. 2021 Apr;9:100123. [PubMed] [Google Scholar]
Iversen K, Bundgaard H, Hasselbalch RB, Kristensen JH, Nielsen PB, Pries-Heje M, Knudsen AD, Christensen CE, Fogh K, Norsk JB, Andersen O, Fischer TK, Jensen CAJ, Larsen M, Torp-Pedersen C, Rungby J, Ditlev SB, Hageman I, Møgelvang R, Hother CE, Gybel-Brask M, Sørensen E, Harritshøj L, Folke F, Sten C, Benfield T, Nielsen SD, Ullum H. Risk of COVID-19 in health-care workers in Denmark: an observational cohort study.Lancet Infect Dis. 2020 Dec;20(12):1401-8. [PubMed] [Google Scholar]
Chen Y, Tong X, Wang J, Huang W, Yin S, Huang R, Yang H, Chen Y, Huang A, Liu Y, Chen Y, Yuan L, Yan X, Shen H, Wu C. High SARSCoV-2 antibody prevalence among healthcare workers exposed to COVID-19 patients. J Infect. 2020 Sep;81(3):420-6. [PubMed] [Google Scholar]
Moscola J, Sembajwe G, Jarrett M, Farber B, Chang T, McGinn T, Davidson KW; Northwell Health COVID-19 Research Consortium. Prevalence of SARS-CoV-2 antibodies in health care personnel in the New York City area. JAMA. 2020 Sep;324:893-5. [PubMed] [Google Scholar]
Steensels D, Oris E, Coninx L, Nuyens D, Delforge ML, Vermeersch P, Heylen L. Hospital-wide SARS-CoV-2 antibody screening in 3056 staff in a tertiary center in Belgium. JAMA. 2020 Jul;324:195-7. [PubMed] [Google Scholar]
Garcia-Basteiro AL, Moncunill G, Tortajada M, Vidal M, Guinovart C, Jiménez A, Santano R, Sanz S, Méndez S, Llupià A, Aguilar R, Alonso S, Barrios D, Carolis C, Cisteró P, Chóliz E, Cruz A, Fochs S, Jairoce C, Hecht J, Lamoglia M, Martínez MJ, Mitchell RA, Ortega N, Pey N, Puyol L, Ribes M, Rosell N, Sotomayor P, Torres S, Williams S, Barroso S, Vilella A, Muñoz J, Trilla A, Varela P, Mayor A, Dobaño C. Seroprevalence of antibodies against SARS-CoV-2 among health care workers in a large Spanish reference hospital. Nat Commun. 2020;11(1):3500.[PubMed] [Google Scholar]
Pallett SJC, Rayment M, Patel A, Fitzgerald-Smith SAM, Denny SJ, Charani E, Mai AL, Gilmour KC, Hatcher J, Scott C, Randell P, Mughal N, Jones R, Moore LSP, Davies GW. Point-of-care serological assays for delayed SARS-CoV-2 case identification among health-care workers in the UK: a prospective multicentre cohort study. Lancet Respir Med. 2020 Sep;8(9):885-94. [PubMed] [Google Scholar]
Eyre DW, Lumley SF, O’Donnell D, Campbell M, Sims E, Lawson E, Warren F, James T, Cox S, Howarth A, Doherty G, Hatch SB, Kavanagh J, Chau KK, Fowler PW, Swann J, Volk D, Yang-Turner F, Stoesser N, Matthews PC, Dudareva M, Davies T, Shaw RH, Peto L, Downs LO, Vogt A, Amini A, Young BC, Drennan PG, Mentzer AJ, Skelly DT, Karpe F, Neville MJ, Andersson M, Brent AJ, Jones N, Martins Ferreira L, Christott T, Marsden BD, Hoosdally S, Cornall R, Crook DW, Stuart DI, Screaton G; Oxford University Hospitals Staff Testing Group, Peto TE, Holthof B, O’Donnell AM, Ebner D, Conlon CP, Jeffery K, Walker TM.Differential occupational risks to healthcare workers from SARS-CoV-2 observed during a prospective observational study. Elife. 2020 Aug 21;9:e60675.[PubMed] [Google Scholar]
Meylan S, Dafni U, Lamoth F, Tsourti Z, Lobritz MA, Regina J, Bressin P, Senn L, Grandbastien B, Andre C, Fenwick C, D’Acremont V, Croxatto A, Guilleret I, Greub G, Manuel O, Calandra T, Pantaleo G, Lazor-Blanchet C; COVID-19 MISS group. SARS-CoV-2 seroprevalence in healthcare workers of a Swiss tertiary care centre at the end of the first wave: a cross-sectional study. BMJ Open. 2021 Jul;11(7):e049232. [PubMed] [Google Scholar]
Parai D, Choudhary HR, Dash GC, Peter A, Saket D, Roy R, Agarwal G, Sahoo S, Rout UK, Nanda RR, Pati S. Seroprevalence of IgG antibody against SARS-CoV-2 among health care workers of anaesthesia departments from various hospital settings in India. medRxiv. 2021 Jan 1. [Google Scholar]
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