Barium Poisoning with Analytical Aspects and its Management


  • Supriya Krishna Chemistry Division, Lok Nayak Jayaprakash Narayan National Institute of Criminology & Forensic Science, Rohini, Delhi, India.
  • AK Jaiswal Department of Forensic Medicine and Toxicology, All India Institute of Medical Sciences, New Delhi, India.
  • Sujata . Department of Toxicology, Chaudhary Charan Singh University, Meerut, Uttar Pradesh, India.
  • M Gupta Department of Pharmacology, All India Institute of Medical Sciences, New Delhi, India.
  • DK Sharma Quality Council of India (Board NABL), Gurugram, Haryana, India.
  • Zahid Ali Department of Forensic Medicine and Toxicology, All India Institute of Medical Sciences, New Delhi, India.


Barium is a non-essential nutrient to terrestrial organisms and reported to be toxic at elevated concentrations. Barium is a heavy divalent alkaline earth metal. It is denoted by the symbol Ba and has an atomic number 56. Barium occurs in nature as baryte ore (Barium Sulphate, BaSO4 ) and witherite ore (Barium Carbonate, BaCO3). Barium is used in various industrial processes. The common-mode is accidental ingestion and the common compound is barium carbonate. Barium carbonate is a highly toxic substance used in the past as Rodenticides. The insoluble form of barium, such as Barium Sulphate, commonly used in radiographic procedures is harmless whereas soluble salts of barium such as barium carbonate are highly toxic. Weakness, paralysis, and hypokalemia being the characteristics signs of the barium poisoning. The clinical features of barium poisoning along with the appropriate diagnosis has been discussed in this paper. The analytical techniques such as Voltammetry, AAS, ICP-OES, NAA, UV-Vis Spectrophotometry can be routinely used to analyze biological and non-biological samples from poisoning as well as overdose cases. This paper can assist officials, toxicologist, physicians and researchers, understand barium poisoning and its management in a much simpler way. 

How to cite this article: Krishna S, Jaiswal AK, Sujata et al. Barium Poisoning with Analytical Aspects and its Management. Int J Adv Res Med Chem 2020; 2(1): 20-27.


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