Clinical Trial of Pippaladi Gutika Anjan in the Management of Arma with Special Reference to Pterygium
Keywords:
Arma, Pippaladi gutika Anjana, lekhana Anjana, pterygiumAbstract
Introduction: Ayurveda is considered the oldest medical science, existing since or before human creation. According to Ayurvedic texts, “Arma” describes a condition where a triangular, wing-like fibro-vascular layer gradually advances towards the “krisna mandala” (cornea) from either the “kaneenika” (inner canthus) or “apanga sandhi” (outer canthus) of the eye. Pterygium, on the other hand, is characterised by a wing- shaped fold of conjunctiva encroaching upon the cornea within the interpalpebral fissure. This condition is degenerative, involving the subconjunctival tissues, and manifests as vascularised granulation tissue invading the cornea, potentially damaging Bowman’s membrane and the superficial stromal layers.
Aims: The aims and objectives of this study are twofold: (i) To review the literature on “Arma” from various Ayurvedic Samhitas and other classical texts, alongside modern reviews on pterygium from contemporary sources, and to analyse conceptual and clinical studies involving patients with pterygium vis-à-vis Arma. (ii) To evaluate the efficacy of “Pippaladi Gutika Anjana” in managing Arma, particularly in relation to pterygium.
Method: In a clinical trial, one hundred patients with Arma were included in a single group. All patients received treatment with Pippaladi Gutika Anjana as a lekhana anjana for 60 days.
Results: The mean scores before the treatment were 1.28, 1.22, 1.04, 1.65, and 1.26, which reduced to 0.35, 0.85, 0.85, 1.06, and 0.90 after 60 days of treatment, in cases of irritation, daha, ragata, foreign body sensation, and mamsa vriddhi, respectively.
Conclusion: The trial compound showed promising symptomatic relief for most clinical features, including the growth of pterygium (Arma). Importantly, no adverse effects of the treatment compound were observed during the trial period.
How to cite this article:
Majumdar A, Das B. Clinical Trial of Pippaladi
Gutika Anjan in the Management of Arma with
Special Reference to Pterygium. J Adv Res Ayur
Yoga Unani Sidd Homeo. 2024;11(3&4): 7-11.
DOI: https://doi.org/10.24321/2394.6547.202402
References
Sastri AD. Sushrut samhita. Vol. 3. Chaukhamba Sanskrit Sansthan; 2019.
Sastri AD. Bhaishajya ratnavali. Vol. 2. Chaukhamba Sanskrit Sansthan; 2019.
Sarma PV. Dravya guna vijnan. Vol. 1. Chaukhamba Bharati Academy; 2013.
Khurana AK. Textbook of ophthalmology. 8th ed. New Age International Publishers; 2022.
