A Case Report of Non-Reactive Psychosis in a COVID-19 Patient
Abstract
Background: COVID-19 causes reactive psychiatric symptoms like anxiety,
depression, insomnia etc besides significant inflammatory response.
A number of COVID-19 patients are found to present with complex
neuropsychiatric syndromes, including the first onset of psychosis, that
seem to be directly related to brain damage in the context of COVID-19.
Most cases of psychotic disorder in COVID-19 patients are being found
in individuals with no personal or family history of mental illness.
Case Description: A 33-year-old man presented with acute restlessness,
agitation, wandering, vandalizing things, suspiciousness, hallucinatory
behaviour, decreased sleep for 3 days duration. There was no past history
or family history of any psychiatric illness. There was a history of mild
grade fever 7 days before the onset of the psychotic symptoms. The
patient was uncooperative, irritable, and had hallucinatory behaviour.
Rapid Antigen Test (RAT) was positive. The patient responded to
injectable antipsychotic haloperidol which was later changed to Tab
Olanzepine 5 mg. The patient developed no COVID symptoms and no
psychotic symptoms were seen further.
Conclusion: There is a possibility of a psychosis break as a COVID-19
clinical presentation, suggesting potential participation of inflammatory
and autoimmunologic phenomena triggered as a response to the
coronavirus infection.
How to cite this article:
Debnath M, Roy B, Chakma P. A Case Report of
Non-Reactive Psychosis in a COVID-19 Patient.
Rec Adv Path Lab Med. 2021;7(1&2):11-13.
References
Kozato N, Mishra M, Firdosi M. New-onset psychosis due to COVID-19. BMJ Case Rep. 2021;14:e242538. [PubMed] [Google Scholar]
Thomas SP. Psychosis related to COVID-19: reports of a disturbing new complication. Issues Ment Health Nurs. 2021;42(2):111. [PubMed] [Google Scholar]
Smith CM, Komisar JR, Mourad A, Kincaid BR. COVID-19-associated brief psychotic disorder. BMJ Case Rep. 2020;13:e236940. [PubMed] [Google Scholar]
Chacko M, Job A, Caston 3rd F, George P, Yacoub A, Cáceda R. COVID-19-induced psychosis and suicidal behavior: case report. SN Compr Clin Med. 2020 Sep;2:2391-5. [PubMed] [Google Scholar]
Zhang K, Shi Y, Liu H, Hashimoto K. A case report of suicide attempt caused by acute and transient psychotic disorder during the COVID-19 outbreak. Case Rep Psychiatry. May 2020;2020:4320647. [PubMed] [Google Scholar]
Elfil M, Selby L, Schooneveld TC, Fadul N. Acute psychosis associated with recent SARS-CoV-2 infection: a case report. IDCases. 2021;24:e01140. [PubMed] [Google Scholar]
Lanier CG, Lewis SA, Patel PD, Ahmed AM, Lewis PO. An unusual case of COVID-19 presenting as acute psychosis. J Pharm Pract. 2020;897190020977721. [PubMed] [Google Scholar]
Ferrando SJ, Klepacz L, Lynch S, Tavakkoli M, Dornbush R, Baharani R, Smolin Y, Bartell A. COVID-19 psychosis: a potential new neuropsychiatric condition triggered by novel coronavirus infection and the inflammatory response? Psychosomatics. 2020 Sep-Oct;61:551-5. [PubMed] [Google Scholar]
Kumar P, Tiwari DS, Patel VK, Vasavada DA. A case report on acute and transient psychotic disorder due to coronavirus disease 2019 quarantine. J Mental Health Hum Behav. 2020;25:152-4. [Google Scholar]
Patel RM, Gupta SD, Sood SV, Malhotra SD, Patel PR. A case report of steroid-induced psychosis in a COVID-19 patient. Innov J Med Health Sci. 2021;1545-8.
Majadas S, Perez J, Casado-Espada NM, Zambrana A, Bullon A, Roncero C. Case with psychotic disorder as a clinical presentation of COVID-19. Psychiatry Clin Neurosci. 2020;74:550-2. [PubMed] [Google Scholar]
Downloads
Published
Issue
Section
License
Copyright (c) 2021 Open Access
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
We, the undersigned, give an undertaking to the following effect with regard to our article entitled
“_______________________________________________________________________________________________________________________________________________________________________________
________________________________________________________________________________” submitted for publication in (Journal title)________________________________________________ _______________________________________________________Vol.________, Year _________:-
1. The article mentioned above has not been published or submitted to or accepted for publication in any form, in any other journal.
2. We also vouchsafe that the authorship of this article will not be contested by anyone whose name(s) is/are not listed by us here.
3. I/We declare that I/We contributed significantly towards the research study i.e., (a) conception, design and/or analysis and interpretation of data and to (b) drafting the article or revising it critically for important intellectual content and on (c) final approval of the version to be published.
4. I/We hereby acknowledge ADRs conflict of interest policy requirement to scrupulously avoid direct and indirect conflicts of interest and, accordingly, hereby agree to promptly inform the editor or editor's designee of any business, commercial, or other proprietary support, relationships, or interests that I/We may have which relate directly or indirectly to the subject of the work.
5. I/We also agree to the authorship of the article in the following sequence:-
Authors' Names (in sequence) Signature of Authors
1. _____________________________________ _____________________________________
2. _____________________________________ _____________________________________
3. _____________________________________ _____________________________________
4. _____________________________________ _____________________________________
5. _____________________________________ _____________________________________
6. _____________________________________ _____________________________________
7. _____________________________________ _____________________________________
8. _____________________________________ _____________________________________
Important
(I). All the authors are required to sign independently in this form in the sequence given above. In case an author has left the institution/ country and whose whereabouts are not known, the senior author may sign on his/ her behalf taking the responsibility.
(ii). No addition/ deletion/ or any change in the sequence of the authorship will be permissible at a later stage, without valid reasons and permission of the Editor.
(iii). If the authorship is contested at any stage, the article will be either returned or will not be
processed for publication till the issue is solved.
