Antimicrobial Potency of Ayurveda Principle based HSP Mixture for Gargling, Steam Inhalation, and Nebulisation in Prevention and Early Management of SARS-COV-2 Disease


  • CD Ravi Raj Ayurveda Physician & CEO, Dr Jains Health Care Services, Savlanga Road, Opp. Karnataka Bank, Shivamogga, Karnataka, India.


Introduction: The SARS-COV-2 disease has become the strongest among all the deadly respiratory diseases in taking the lives of lakhs of humans. The current study adopts the Ayurvedic principle of Samprapti Vighatana i.e. arresting the pathogenesis, through the usage of a novel selfformulated medicine powder named Haridradi Steam Powder (HSP)
which is an anti-microbial decoction used for gargling, steam inhalation therapy, and nebulisation in the prevention of SARS-COV-2 disease by reducing the viral load in patients.

Methodology: Haridradi Steam Powder (HSP) containing decoction for gargling, steam, and nebulisation by adding 3% normal saline were prepared and given to the -participants as per self-made protocol i.e. gargling was advised for primary contacts, asymptomatic patients, and healthy persons as a preventive tool. High-pressure steam inhalation
was advised for mild to moderate symptomatic patients and 3% normal saline nebulisation was advised for moderate symptomatic patients.

Results: Out of the total of 30 cases, comprising 22 primary contacts, 3 HRCT atypical viral pneumonia with severity score from 8 to 16, 3 RTPCR positive patients, and 2 RT-PCR positive patients with HRCT score, a marked improvement was seen in more than 20 subjects within a short span of time.

Conclusion: The treatment formulation HSP Mixture is found to be effective yet simple, safe, and cost-effective, and is used in different therapies in the prevention and management of early SARS-COV-2 disease.

How to cite this article:
Raj CDR. Antimicrobial Potency of Ayurveda Principle based HSP Mixture for Gargling, Steam Inhalation, and Nebulisation in Prevention and Early Management of SARS-COV-2 Disease. J Adv Res Ayur Yoga Unani Sidd Homeo. 2021; 8(1&2): 10-13.



Dairaku I, Han Y, Yanaka N, Kato N. Inhibitory effect of curcumin on IMP dehydrogenase, the target for

anticancer and antiviral chemotherapy agents. Biosci Biotechnol Biochem. 2010;74(1):185-7. [PubMed] [Google Scholar]

Singh RK, Rai D, Yadav D, Bhargava A, Balzarini J, Clercq ED. Synthesis, antibacterial and antiviral properties of

curcumin bioconjugates bearing dipeptide, fatty acids and folic acid. Eur J Med Chem. 2010;45(3):1078-86. [PubMed] [Google Scholar]

Chen DY, Shien JH, Tiley L, Chiou SS, Wang SY, Chang TJ, Lee YJ, Chan KW, Hsu WL. Curcumin inhibits influenza

virus infection and haemagglutination activity. Food Chem. 2010;119(4):1346-51. [Google Scholar]

Antonio AS, Wiedemann LSM, Veiga-Junior VF. Natural products’ role against COVID-19. RSC Adv. 2020;10:23379. [Google Scholar]

Trikamji J. Sushrutha: Sushrutha Samhita with commentary of Dalhana. 40th Chapter, Verse 63-65. Chikitsa Sthana, Varanasi: Chowkhambha Surabharthi Prakashan, 2009. p. 553, 824.

Satomura K, Kitamura T, Kawamura T, Shimbo T,Watanabe M, Kamei M, Takano Y, Tamakoshi A, Great Cold Investigators-I. Prevention of upper respiratory tract infections by gargling: a randomized trial. Am J Prev Med. 2005 Nov;29(4):302-7. [PubMed] [Google Scholar]

O’Donnell VB, Thomas D, Stanton R, Maillard JY, Murphy RC, Jones SA, Humphreys I, Wakelam MJO, Fegan C,

Wise MP, Bosch A, Sattar SA. Potential Role of Oral Rinses Targeting the Viral Lipid Envelope in SARS-CoV-2

Infection. Function (Oxf). 2020;1(1). [PubMed] [Google Scholar]

Meister TL, Bruggemann Y, Todt D, Conzelmann C, Muller JA, Grob R, Munch J, Krawczyk A, Steinmann J, Steinmann J, Pfaender S, Steinmann E. Virucidal Efficacy of Different Oral Rinses Against Severe Acute Respiratory Syndrome Coronavirus 2. J Infect Dis. 2020 Sep;222(8):1289-92. [PubMed] [Google Scholar]

Vathanophas V, Pattamakajonpong P, Assanasen P, Suwanwech T. The effect of steam inhalation on nasal obstruction in patients with allergic rhinitis. Asian Pac J Allergy Immunol. 2019. [PubMed] [Google Scholar]

Sahin ONA, Gülen F. Approach to common cold in children. J Ped Res. 2015;2(1):1-6.

Szilagyi PG. Humidifiers and other symptomatic therapy for children with respiratory tract infections. Pediatr Infect Dis J. 1991;10(6):478-9. [PubMed]

Uy TMZ, Miranda MCB, Aro SJV, Uy MEV. Should steam inhalation be used in the treatment and prevention of COVID-19? Asia Pac Center Evid Based Healthcare. 2020;1:1-6. [Google Scholar]

Lowen AC, Mubareka S, Steel J, Palese P. Influenza virus transmission is dependent on relative humidity and temperature. PLoS Pathog. 2007;3(10):1470-6. [PubMed] [Google Scholar]

Chin AWH, Chu JTS, Perera MRA, Hui KPY, Yen HL, Chan MCW, Peiris M, Poon LLM. Stability of SARSCoV-2 in different environmental conditions. Med Rxiv. 2020;1:10. [Google Scholar]

Umoren R, Odey F, Meremikwu MM. Steam inhalation or humidified oxygen for acute bronchiolitis in children

up to three years of age. Cochrane Database Syst Rev. 2011;(1):CD006435. [PubMed] [Google Scholar]

Gupta HV, Gupta VV, Kaur G, Baidwan AS, George PP, Shah JC, Shinde K, Malik R, Chitkara N, Bajaj KV. Effectiveness of 3% hypertonic saline nebulization in acute bronchiolitis among Indian children: A quasiexperimental study. Perspect Clin Res. 2016 Apr-Jun;7(2):88-93. [PubMed] [Google Scholar]

Li Q, Guan X, Wu P, Wang X, Zhou L, Tong Y, Ren R, Leung KSM, Lau EHY, Wong JY, Xing X, Xiang N, Wu Y, Li C, Chen

Q, Li D, Liu T, Zhao J, Liu M, Tu W, Chen C, Jin L, Yang R, Wang Q, Zhou S, Wang R, Liu H, Luo Y, Liu Y, Shao G, Li H, Tao Z, Yang Y, Deng Z, Liu B, Ma Z, Zhang Y, Shi G, Lam TTY, Wu JT, Gao GF, Cowling BJ, Yang B, Leung GM, Feng Z. Early transmission dynamics in Wuhan, China, of Novel Coronavirus-infected pneumonia. N Engl J Med. 2020;382(13):1199-207. [PubMed] [Google Scholar]

He X, Lau EHY, Wu P, Deng J, Wang J, Hao X, Lau YC, Wong JY, Guan Y, Tan X, Mo X, Chen Y, Liao B, Chen W, Hu F, Zhang Q, Zhong M, Wu Y, Zhao L, Zhang F, Cowling BJ, Li F, Leung GM. Temporal dynamics in viral shedding and transmissibility of COVID-19. Nat Med. 2020;26(5):672-5. [PubMed] [Google Scholar]

Swain SK, Sahu A. Steam inhalation as an adjuvant treatment in Covid-19 positive health care professionals: Our Experiences at Tertiary Care Teaching Hospital. Int J Cur Res Rev. 2021;13(5). [Google Scholar]