Comparative Study to Compare the Efficacy and Safety of a Unani Pharmacopoeial Formulations-UNIM-001+UNIM-003 with Methoxsalen in Cases of Bars (Vitiligo) - A Preliminary Study

Authors

  • Parvez Khan Regional Research Institute of Unani Medicine (CCRUM), Aligarh, Uttar Pradesh, India. https://orcid.org/0000-0001-6380-002X
  • Radhey Shyam Verma Regional Research Institute of Unani Medicine (CCRUM), Aligarh, Uttar Pradesh, India.
  • Sadia Ayub Regional Research Institute of Unani Medicine (CCRUM), Aligarh, Uttar Pradesh, India.
  • Sheereen Afza Regional Research Institute of Unani Medicine (CCRUM), Aligarh, Uttar Pradesh, India.
  • Jamal Akhtar Central Council for Research in Unani Medicine, Jawaharlal Nehru Anusandhan Bhavan, New Delhi, India.
  • Asim Ali Khan Central Council for Research in Unani Medicine, Jawaharlal Nehru Anusandhan Bhavan, New Delhi, India.

Abstract

Background: Vitiligo is a prevalent acquired disorder of skin depigmentation in changeable patterns, differing from small macules with scalloping borders to near total depigmentation of body. The disorder involves nearly 1% to 2% of the world population regardless of race and ethnicity with highest incidence recorded in Indian subcontinent followed by Mexico and Japan.

Methodology: A Unani formulation UNIM-001+ UNIM-003 was procured from Central Council for Research in Unani Medicine, New Delhi. Melanocyl Tablet (10mg each) (Methoxsalen) was purchased from Aligarh. Sixty Five patients of Trail group (UNIM-001+ UNIM-003) and sixty seven patients of control group (Comparator group) of 12-50 years of either sex were selected from the lot of patients attending the Out Patient Department (OPD). The patients were instructed to expose themselves to sunlight half an hour to two hours after ingestion of oral drugs. Data were analyzed statistically by one-way analysis of variance (ANOVA) followed by Dennett’s’ test. The values were considered significant when the P-value was found less than 0.05.

Result: UNIM-001 Tablet and UNIM-003 topical drug as well as comparator Drug (Melanocyl Tablet (Methoxsalen)) did not induce any negative or unfavorable response.

Conclusion: UNIM-001 Tablet and UNIM-003 topical drug as well as comparator Drug (Melanocyl Tablet (Methoxsalen)) Possesses anti-Vitiligo effect.

How to cite this article:
Khan P, Verma RS, Ayub S, Afza S, Akhtar J, Khan AA. Comparative Study to Compare the Efficacy and Safety of a Unani Pharmacopoeial Formulations-UNIM-001+UNIM-003 with Methoxsalen in Cases of Bars (Vitiligo) - A Preliminary Study. J Adv Res Ayur Yoga Unani Sidd Homeo 2020; 7(3&4): 16-26.

DOI: https://doi.org/10.24321/2394.6547.202009

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Published

2020-12-27