How Soon after Blood Transfusion can the Haemoglobin Value be Estimated among Not Actively Bleeding Children?
Keywords:
Blood transfusion, packed red blood cell, haemoglobin.Abstract
Introduction: The main target of blood transfusion in children is to prevent unnecessary deaths, and ameliorate their health. After a blood transfusion, haemoglobin (Hb) estimation is necessary to assess its success. This study’s objective was to assess the earliest time after blood transfusion for the estimation of the Hb value among not actively bleeding children. The ability to quickly estimate the rise inHb value after transfusion is essential in managing outpatients and acutely ill children.
Methods: Children aged 1 month to 18 years were included in this prospective observational study conducted from January 2023 to July 2023 at the Paediatric Department of BCM Hospital, Sitapur in Uttar Pradesh, India. Three different periods of Hb measurement: pre-transfusion, 15 minutes after transfusion, and 6–8 hours after transfusion were compared using the paired Student’s t-test. Twotailed p values less than 0.05 were considered significant.
Results: During the course of the study, a total of 94 children (72 males and 22 females) were given packed red blood cell (PRBC) transfusions. Comparison between mean Hb values at 15 minutes after transfusion (mean = 10.4, SD = 1.8) and 6–8 hours after transfusion (mean = 10.4, SD = 1.9) showed statistically no significant difference (t = 0.2751, df = 93, p = 0.7838).
Conclusion: After a blood transfusion,15 minutes is the earliest time after which haemoglobin value can be estimated among not actively bleeding children.
How to cite this article:
Kumar S, Cynthia S. How Soon after Blood Transfusion can the Haemoglobin Value be Estimated among Not Actively Bleeding Children?. J Adv Res Med Sci Tech. 2023; 10(3&4):
1-5.
References
Napolitano LM, Kurek S, Luchette FA, Corwin HL, Barie PS, Tisherman SA, Hebert PC, Anderson GL, Bard MR, Bromberg W, Chiu WC, Cipolle MD, Clancy KD, Diebel L, Hoff WS, Hughes KM, Munshi I, Nayduch D, Sandhu R, Yelon JA; American College of Critical Care Medicine of the Society of Critical Care Medicine; Eastern Association for the Surgery of Trauma Practice Management Workgroup. Clinical practice guideline: red blood cell transfusion in adult trauma and critical care. Crit Care Med. 2009 Dec;37(12):3124-57.
[PubMed] [Google Scholar]
Chassé M, English SW, McIntyre L, Knoll G, Shehata N, Forster A, Wilson K, van Walraven C, Tinmouth A, Fergusson DA. Effect of blood donor characteristics on transfusion outcomes: a protocol for systematic review and meta-analysis. Syst Rev. 2014 Mar 20;3:28. [PubMed] [Google Scholar]
Surgenor DM, Wallace EL, Hao SH, Chapman RH. Collection and transfusion of blood in the United States, 1982-1988. N Engl J Med. 1990 Jun 7;322(23):1646-51. [PubMed] [Google Scholar]
Wallace EL, Surgenor DM, Hao HS, An J, Chapman RH, Churchill WH. Collection and transfusion of blood and blood components in the United States, 1989. Transfusion. 1993 Feb;33(2):139-44. [PubMed] [Google Scholar]
Raat NJ, Ince C. Oxygenating the microcirculation: the perspective from blood transfusion and blood storage. Vox Sang. 2007 Jul;93(1):12-8. [PubMed] [Google Scholar]
Vincent JL, Piagnerelli M. Transfusion in the intensive care unit. Crit Care Med. 2006 May;34(5 Suppl):S96-101. [PubMed] [Google Scholar]
Tinmouth A, Fergusson D, Yee IC, Hébert PC; ABLE Investigators; Canadian Critical Care Trials Group. Clinical consequences of red cell storage in the critically ill. Transfusion. 2006 Nov;46(11):2014-27. [PubMed] [Google Scholar]
Lelubre C, Vincent JL. Red blood cell transfusion in the critically ill patient. Ann Intensive Care. 2011 Oct 4;1:43. [PubMed] [Google Scholar]
Wiesen AR, Hospenthal DR, Byrd JC, Glass KL, Howard RS, Diehl LF. Equilibration of hemoglobin concentration after transfusion in medical inpatients not actively bleeding. Ann Intern Med. 1994 Aug 15;121(4):278-30. [PubMed] [Google Scholar]
Elizalde JI, Clemente J, Marín JL, Panés J, Aragón B, Mas A, Piqué JM, Terés J. Early changes in hemoglobin and hematocrit levels after packed red cell transfusion in patients with acute anemia. Transfusion. 1997 Jun;37(6):573-6. [PubMed] [Google Scholar]
Linda R, Ninda D. Differences in changes of hemoglobin between 6-12 hours and 12-14 hours after transfusion. Indones J Clin Pathol Med Lab. 2018 Sep 30;24(2):108-11. [Google Scholar]
Hoque MM, Adnan SD, Karim S, Al Mamun MA, Nandy S, Faruki MA, Mahmud K, Islam K. Equilibration and increase of hemoglobin concentration after one unit whole blood transfusion among patients not actively bleeding. J Dhaka Med Coll. 2014 Oct;23(2):161-6.
[Google Scholar]
Audu LI, Otuneye AT, Mairami AB, Mshelia LJ, Nwatah VE. Posttransfusion haematocrit equilibration: timing posttransfusion haematocrit check in neonates at the National Hospital, Abuja, Nigeria. Int J Pediatr. 2015;2015:175867. [PubMed] [Google Scholar]
Carson JL, Duff A, Poses RM, Berlin JA, Spence RK, Trout R, Noveck H, Strom BL. Effect of anaemia and cardiovascular disease on surgical mortality and morbidity. Lancet. 1996 Oct 19;348(9034):1055-60. [PubMed] [Google Scholar]
Mudumbai SC, Cronkite R, Hu KU, Wagner T, Hayashi K, Ozanne GM, Davies MF, Heidenreich P, Bertaccini E. Association of admission hematocrit with 6-month and 1-year mortality in intensive care unit patients. Transfusion. 2011 Oct;51(10):2148-59. [PubMed] [Google Scholar]
Sakr Y, Lobo S, Knuepfer S, Esser E, Bauer M, Settmacher U, Barz D, Reinhart K. Anemia and blood transfusion in a surgical intensive care unit. Crit Care. 2010;14(3):R92. [PubMed] [Google Scholar]
Vincent JL. Indications for blood transfusions: too complex to base on a single number? Ann Intern Med.2012 Jul 3;157(1):71-2. [PubMed] [Google Scholar]
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