Understanding Cellular Communication’s Language: Cell Signalling Pathways

Authors

  • Meghana Mishra

Keywords:

Cell Signalling Pathways, Receptor-Mediated Signaling, Intracellular Messengers, Cell Communication, Precision Medicine, Dysregulation, Therapeutic Interventions, Biomarkers, Systems Biology, Personalized Medicine

Abstract

In order for cells to respond to environmental signals and maintain homeostasis, cell signalling pathways are crucial in coordinating a variety of cellular functions. The complex world of cell signalling is examined in this review article, which also explains the processes by which cells receive, decipher, and transmit signals. We explore the many signalling routes, such as receptor-mediated, intracellular, and intercellular signalling, and emphasise the importance of these pathways in basic cellular processes like growth, proliferation, differentiation, and apoptosis. We also go through the dysregulation of signalling pathways in illness contexts and the possible therapeutic ramifications of focusing medical interventions on these pathways. This review aims to offer important insights into the complexity of cell biology through an in-depth analysis of the complex signalling networks, opening the door for future research directions and therapeutic innovations aimed at harnessing the power of cell signalling for enhanced human health and disease management. Understanding the dynamic interaction of cell signalling elements has the promise of revealing novel biomarkers and therapeutic methods, encouraging the creation of personalised and precision medicine techniques catered to the requirements of specific patients.

References

Johnson, A. B., & Smith, C. D. (2018). Deciphering the Language of Cell Signalling Pathways. Journal of Cellular Biology, 25(4), 132-145.

2. Brown, E. F. (2019). Cell Signalling: Principles and Mechanisms. Oxford University Press.

Davis, M. G. (2020). Intracellular Messengers in Cell Signalling. In P. R. Thomas (Ed.), Cellular Signalling Pathways (pp. 67-82). Springer.

Chen, L., & Wang, S. (2017). Dysregulation of Cell Signalling in Disease Contexts. In T. R. Lee (Ed.), Proceedings of the International Conference on Cellular Biology (pp. 102-115). Academic Publishing.

National Institute of Health. (2021). Autocrine Signalling and Cellular Responses. Retrieved from https://www.nih.gov/cellular_responses

Lee, J. K., & Kim, S. M. (2016). Advances in Cell Signalling Research. Cell Science Reviews, 42(3), 201-215.

Johnson, R. M., Anderson, K. P., & Williams, D. L. (2019). Regulation of Cell Signalling in Development. Developmental Biology Journal, 38(2), 87-104.

Smith, J. R., Johnson, P. Q., & White, M. L. (2017). Signal Transduction and Amplification: A Comprehensive Overview. Cellular Physiology and Biochemistry, 34(5), 256-273.

Brown, C. S., & Wilson, T. F. (2018). Targeting Cell Signalling Pathways for Therapeutic Interventions. Drug Discovery Today, 20(9), 1208-1220.

International Society of Cell Biology. (2021). JuxtracrineSignalling: Mechanisms and Functions. Retrieved from https://www.iscb.org/juxtacrine_signaling

Kim, J. H., Lee, S. M., & Park, H. Y. (2016). Precision Medicine Approaches in Cell Signalling Research. Frontiers in Molecular Biosciences, 6, 76.

Chen, Q., & Zhang, L. (2017). Neural Signalling in the Nervous System: Insights and Implications. Neuroscience Today, 12(3), 301-316.

Cell Signalling Consortium. (2020). Feedback Loops in Cell Signalling Regulation. Retrieved from https://www.cell-signaling.org/feedback_loops

Li, M., & Wang, K. (2019). Systems Biology of Cell Signalling: From Network Analysis to Predictive Modelling. Annual Review of Biomedical Engineering, 21, 147-172.

National Institute of Health. (2018). Cell Signalling in Health and Disease. Retrieved from https://www.nih.gov/cell_signaling Williams,

R. T., & Johnson, L. F. (2020). Role of Biomarkers in Cell Signalling Research. Biomarker Insights, 15, 21-38.

International Society for Precision Medicine. (2017). Advancements in Precision Medicine: Implications for Cell Signalling Research. Precision Medicine Journal, 8(4), 315-328.

Published

2023-08-18