Basics of Pharmaceutical Emulsion: A Review
Abstract
Pharmaceutical formulations are usually supplied in the form of emulsions for treating skin disorders and skin protection. This method of pharmaceutical treatment is thermodynamically unstable and needs to be stabilized by the application of an emulsifier. Emulsified solutions vary from lotions that have relatively low viscosity to more viscous creams. There are two basic types of emulsion, oil in the Water (O/W), and oil (W/O) water, respectively. Besides these two forms, there is another fairly complex emulsion, called multiple emulsions. Generally, emulsions have some benefits over certain types of treatment, as the solubilized drug could be more bioavailable. Besides, gastrointestinal problems and metabolic effect at the first pass are also avoided, oil in water (O/W), water in oil (W/O).
How to cite this article: Pooni N. Basics of Pharmaceutical Emulsion: A Review. J Durg Dis Dev 2019; 3(2): 10-12.
References
Nimberkar TP, Wanjari BE, Sanghi DK et al. Formulation and Evaluation of Sustained Release Multiple Emulsion of Hydroxy progesterone. Int J Pharm and Pharm.
Vyas SP, Khar RK. Targeted & Controlled Drug Delivery-Novel Carrier Systems. CBS Publishers & Distributors, 1st Edtn.
Herbert AL, Martin MR, Gilbert SB. Pharmaceutical Emulsions and Microemulsions, Pharmaceutical Dosage Forms Disperse Systems. Marcel Dekker, INC, New York and Basel, USA. 1996.
Javed A, Sanjula B, Alka A. Emulsion. Available at: http//Javed- Ali.Tripod.Com. John EH (1976). Dispensing of Medication, Mack Publishing Company. 2008.
Nasirideen S, Kas HS, Oner F et al. Naproxen incorporated lipid emulsions. I. Formulation and stability studies. J Clinical Pharma Therapeut 1998.
Nita A, Rouzhou H, Richard AW. Performance of a rotating membrane emulsifier for production of coarse droplets. J Membrane 2009.
Lachman L, Lieberman HA. The Theory & Practice of Industrial Pharmacy. CBS Publishers & Distributors. 2009.
Kumar R, Kumar M, Mahadevan N. Multiple Emulsions: A Review. Int J Recent Adv Pharm Research.
Jain NK. Advances in Controlled and Novel Drug Delivery. CBS Publishers & Distributors, 1st Edtn.
Cerpnjak K, Zvonar A, Gašperlin M et al. Lipid-based systems as a promising approach for enhancing the bioavailability of poorly water-soluble drugs.
Odriozola-Serrano I, Oms-Oliu G, Martín-Belloso O. Nano emulsion-based delivery systems to improve functionality of lipophilic components.
Mc Clements DJ. Nano emulsion-based oral delivery systems for lipophilic bioactive components: nutraceuticals and pharmaceuticals.
Wu Y, Li YH, Gao XH, Chen HD. The application of nano emulsion in dermatology: an overview. J Drug Target.
Kotta S, Khan AW, Pramod K et al. Exploring oral nano emulsions for bioavailability enhancement of poorly water-soluble drugs. Expert Opin Drug Deliv.
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