A Review on the Herbal Plants used in the Treatment of Peptic Ulcer
Abstract
A peptic ulcer is a mostly occurring disease of the gastrointestinal tract that is commonly acidic. Formation of Peptic ulcer occurred due to excess of acid, in gastric juice peptic activity by a breakdown in mucosal defenses. Some of anti-ulcer medicines such as H2 receptor antagonists and proton pump inhibitors are used for the treatment of ulcer. However, these drugs have shown disease relapse, drug interactions, and side effects. Many medicinal plants have found useful in the treatment of peptic ulcer. The purpose of this review is to know more about the anti-ulcer properties of the medicinal plants, and about some medicinal plant which used in the treatment of ulcer disease such as Aloe vera (L.), Rhizophora mangle L, Ocimum sanctum Linn, Glycyrrhiza glabra, Asparagus racemosus Willd. By their mechanisms these plants were studied underlying to the gastroprotective effect.
How to cite this article: Pandey A. A Review on the Herbal Plants used in the Treatment of Peptic Ulcer. J Durg Dis Dev 2019; 3(2): 7-9.
References
Dashputre NL, Naikwade NS. Evaluation of Anti-Ulcer Activity of Methanolic Extract of Abutilon indicum Linn Leaves in Experimental Rats. International Journal of Pharmaceutical Sciences and Drug Research 2011; 3(2): 97-100.
Izzo A, Borrelli F. The Plant Kingdom as a Source of Antiulcer Remedies. Phytother Res 2000; 14: 581–591.
Baron J, Calam J. ABC of the Upper Gastrointestinal Tract: Pathophysiology of Duodenal and Gastric Ulcer and Gastric Cancer. B M J 2001; 323: 980-982.
Manan MJA, Khan M, Safwan AKM et al. Anti-ulcer activity of Ficus religiosa stem bark Ethanolic extract in rats. Journal of Medicinal Plants Research 2011; 5(3): 354-359.
Nayaka H, Nanjundaiah M, Siddaraju et al. Gastroprotective Effect of Ginger Rhizome (Zingiber officinale) Extract: Role of Gallic Acid and Cinnamic Acid in H+, K+ATPase/H. pylori Inhibition and Anti-Oxidative Mechanism. Hindawi Publishing Corporation Evidence- Based Complementary and Alternative Medicine. 2011; 1(1): 1-13.
Vanisree AJ, Shyamala DCS, Mahendran P. The Antiulcer Activity of Garcinia cambogia Extract against Indomethacin Induced Gastric Ulcer in Rats. Phytotherapy Research 2002; 16: 80–83.
Srivastava DP, Rajani GP, Gupta N et al. Antiulcer, and Anti-inflammatory activity of fresh Leaves Extracts of Polyalthia Longifolia In Rats. International Journal of Drug Development & Research 2011; 3(1): 351-359.
Vinay SC, Pushpesh KM, Rakesh M et al. Allophylus serratus: a plant with potential anti-ulcerogenic activity. Journal of Ethnopharmacology 2005; 99: 361–366
Sharma TR, Shilpi A. Multiple biological activities of aloe barbadensis (aloe vera): an overview. Asian Journal of Pharmacy & Life Science 2011; 1(2).
Sai KB, Radha KL, Gowrinath RM. Anti-ulcer effect of Aloe vera in non-steroidal anti-inflammatory drug-induced peptic ulcers in rats. African Journal of Pharmacy and Pharmacology 2011; 5(16).
Justin RS, Joseph B. Pharmacognostic and phytochemical properties of Aloe vera linn – an overview. International Journal of Pharmaceutical Sciences Review and Research 2010; 4(2)
Roig JT. Medicinal, aromatic, and dangerous plants from Cuba. Editorial Revolución y Progreso, La Habana,
; 745.
Escobar A, Varcalcel L, Noa M et al. Polyphenol and phytosterols. Composition in an antibacterial extract from Rhizophora mangle L.´s bark. J Herbal Pharmacother 2008b; 7: 107-128.
Antonia RM, Arturo E, Betty M et al. Pharmacological and toxicological evaluation of Rhizophora mangle L., as a potential antiulcerogenic drug: Chemical composition of the active extract. Journal of Pharmacognosy and Phytotherapy 2010; 2(4): 56-63.
Luiz-Ferreira A, Almeida ACA, de-Faria FM et al. Antioxidant action of mangrove polyphenols against gastric damage induced by absolute ethanol and ischemia-reperfusion in the rat. The Scientific World Journal 2012.
Qu´ilez A, Berenguer B, Sanchez LM et al. Protective and antioxidant effects of Rhizophora mangle L. against NSAID induced gastric ulcers. Journal of Ethnopharmacology 2006; 103(2): 194–200.
Branford-White C, de Armas E, Marrero E et al. Efficacy of Rhizophora mangle aqueous bark extract (RMABE) in the treatment of aphthous ulcers: a pilot study. Current Medical Research and Opinion 2005; 21(11): 1711–1715.
Alba RMSB, Ana CAA, Luiz-Ferreira A et al. Effects of Rhizophora mangle on Experimental Colitis Induced by TNBS in Rats. Evidence Based Complementary and Alternative Medicine, 2012.
Govind P, Madhuri S. Pharmacological activities of Ocimum Sanctum (tulsi): a review. International Journal of Pharmaceutical Sciences Review and Research 2010; 5(1)
Khare CP. Encyclopedia of Indian Medicinal Plants. New York: Springer-Verlag. 2004; 233-5.
Mazumder PM, Farswan M, Parcha V et al. Hypoglycaemic and antioxidant activity of an isolated compound from Ficus arnottiana bark. Pharmacologyonline. 2008
Carvalho AC, Guedes MM, De Souza AL et al. Gastroprotective effect of mangiferin: A xanthonoid from Mangifera indica, against gastric injury induced by ethanol and indomethacin in rodents. Planta Med 2007; 73: 1372–6.
Araújo LX, Novato, TP, Zeringota V et al. Acaricidal activity of thymol against larvae of Rhipicephalus microplus (Acari: Ixodidae) under semi-natural conditions. Parasitol Res 2015; 114: 3271-3276.
Sagradas J, Costa G, Figueirinha A et al. Gastroprotective effect of Cymbopogon citratus infusion on acute ethanolinduced gastric lesions in rats. J Ethnopharmacol 2015; 173: 134-138.
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