Pomegranate as an Antibacterial Agent against Pathogens and at the same Time Advantageous to Beneficial Bacteria: A Review
Abstract
Pomegranate contains several categories of bioactive constituents such as anthocyanins, flavonols, flavanols, isoflavones, flavones, hydrolysable and non-hydrolysable tannins that possess strong antioxidant, antibacterial and anti-inflammatory properties. Researches showed that pomegranate’s juice, extracts and isolated compounds are effective against various pathogens, as Clostridium, Escherichia coli, Aggregatibacter, Acinetobacter, Bacillus, Helicobacter, Porphyromonas, Acinetobacter, Cryptococcus, Citrobacter, Alcaligenes, Prevotella, Bacteroids, Cronobacter, Achromobacter, Prevotella, Proteus, Enterococcus, Yersinia, Treponema, Serratia, Klebsiella, Mycobacterium, Lysteria, Pseudomonas, Shigella, Streptococcus, Staphylococcus, Salmonella and Vibrio giving results in many cases comparable or even better than the commercial antibiotics. Pathogens are causing several infections with different scale of severity. Pomegranate’s phytochemicals possess more than one bioactivities and thus it can treat such health issues by more than one ways, affecting more than one parameters associated to them. For example, in cases of bacteria that are causing inflammation, pomegranate is not only killing the bacteria but also by its anti-inflammatory and antioxidant activity is treating the infections caused by them, achieving faster health rather than just removing the infection’s reason (the bacteria). Even pomegranate is bactericidal towards pathogens, it is protecting and enhancing the growth of gut microbiota that is important for health maintenance. Safety tests showed that pomegranate is safe in contrast with antibiotics that are having side effects and are disturbing gut microbiota causing dysbiosis and other disorders indicating that in cases that the antibacterial activity of pomegranate is comparable to antibiotics’ activity, it could be considered as a promising alternative antibacterial agent.
How to cite this article:
Stefanou V, Tsakni A, Timbis D, Vougiouka PA, Doumi I, Maronikolaki I et al. Pomegranate as an Antibacterial Agent against Pathogens and at the same Time Advantageous to Beneficial Bacteria: A Review. Int J Adv Res MicroBiol Immunol 2020; 2(2): 1-13.
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