Giant Cell Reparative Granuloma Presented as Nasal Mass: A Rare Entity


  • Sampa Choudhury Assistant Professor, Department of Pathology, Andaman & Nicobar Islands Institute of Medical Sciences, Port Blair, Andaman & Nicobar Islands.
  • Sharbori Kundu Post Graduate Trainee, Department of Surgery, Midnapore Medical College and Hospital, Midnapore, West Bengal, India.


Giant Cell Reparative Granuloma (GCRG) is an unusual non-neoplastic
lesion which most commonly involves maxilla and mandible. We
present a case of GCRG of the nasal cavity in a young female presented
with the complaint of progressively nasal obstruction. Radiological
findings are usually nonspecific in this entity, therefore a good clinical,
radiological and pathological correlation is needed for final diagnosis
and to differentiate it from other giant cell lesions. Surgical excision is
the preferred treatment modality over simple curettage.


How to cite this article:
Choudhury S, Kundu S. Giant Cell Reparative
Granuloma Presented as Nasal Mass: A Rare
Entity. Rec Adv Path Lab Med. 2021;7(1&2):1-3.


Garg P, Jain J, De N, Chatterjee K. A central giant cell granuloma in posterior part of maxilla- a case report. Int J Surg Case Rep. 2017;30:222-5. [PubMed] [Google Scholar]

Lingaiah J, Ganji L, Yella S, Thatikonda KR. A rare case of reparative granuloma of nasal cavity. Int J Otolaryngol Head Neck Surg. 2014;3:293-7. [Google Scholar]

Williams JC, Thorell WE, Treves JS, Fidler ME, Moore GF, Leibrock LG. Giant cell reparative granuloma of the petrous temporal bone: a case report and literature review. Skull Base Surg. 2000;10:89-93. [PubMed] [Google Scholar]

Morris JM, Lane JI, Witte RJ, Thompson DM. Giant cell reparative granuloma of the nasal cavity. AJNR Am J Neuroradiol. 2004;25:1263-5. [PubMed] [Google Scholar]

Ishinaga H, Otsu K, Mouri G, Takeuchi K. Aggressive giant cell reparative granuloma of the nasal cavity. Case Rep Otolaryngol. 2013;2013:690194. [PubMed] [Google Scholar]

Jamil OA, Lechpammer M, Prasad S, Litvack Z, Dunn IF. Giant cell reparative granuloma of the sphenoid: case report and review of the literature. Surg Neurol Int. 2012;3:140. [PubMed] [Google Scholar]

Yu JL, Qu LM, Wang J, Huang HY. Giant cell reparative granuloma in the temporal bone of the skull base: report of two cases. Skull Base. 2010;20:443-8. [PubMed] [Google Scholar]

Gulati D, Bansal V, Dubey P, Pandey S, Agrawal A. Central giant cell granuloma of posterior maxilla: first expression of primary hyperparathyroidism. Case Rep Endocrinol. 2015;2015:170412. [PubMed] [Google Scholar]

Bovee J, Andrea C. Bone tumors. In: Mills SE, Greenson JK, Hornick JL, Longacre TA, Reuter VE, editors. Sternberg’s Diagnostic Surgical Pathology. 6th ed. Philadelphia: Lippincott Williams & Wilkins; 2015. p. 297-9.