A Case Report of Non-Reactive Psychosis in a COVID-19 Patient
Background: COVID-19 causes reactive psychiatric symptoms like anxiety,
depression, insomnia etc besides significant inflammatory response.
A number of COVID-19 patients are found to present with complex
neuropsychiatric syndromes, including the first onset of psychosis, that
seem to be directly related to brain damage in the context of COVID-19.
Most cases of psychotic disorder in COVID-19 patients are being found
in individuals with no personal or family history of mental illness.
Case Description: A 33-year-old man presented with acute restlessness,
agitation, wandering, vandalizing things, suspiciousness, hallucinatory
behaviour, decreased sleep for 3 days duration. There was no past history
or family history of any psychiatric illness. There was a history of mild
grade fever 7 days before the onset of the psychotic symptoms. The
patient was uncooperative, irritable, and had hallucinatory behaviour.
Rapid Antigen Test (RAT) was positive. The patient responded to
injectable antipsychotic haloperidol which was later changed to Tab
Olanzepine 5 mg. The patient developed no COVID symptoms and no
psychotic symptoms were seen further.
Conclusion: There is a possibility of a psychosis break as a COVID-19
clinical presentation, suggesting potential participation of inflammatory
and autoimmunologic phenomena triggered as a response to the
How to cite this article:
Debnath M, Roy B, Chakma P. A Case Report of
Non-Reactive Psychosis in a COVID-19 Patient.
Rec Adv Path Lab Med. 2021;7(1&2):11-13.
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