Emerging Technologies in Transdermal Drug Delivery
Keywords:
Transdermal, Drug Delivery, solid lipid nanoparticles, MicroneedlesAbstract
Transdermal drug delivery (TDD) represents a promising alternative to traditional oral and injectable routes, offering non-invasive, controlled, and sustained administration of therapeutic agents. The various advanced TDD techniques, including microneedles, iontophoresis, sonophoresis, and nanotechnology-based systems, which address the inherent challenges of skin permeability and drug stability. Microneedles, including coated, dissolving, and hydrogel-forming types, enhance drug delivery through minimally invasive means, improving patient compliance. Iontophoresis utilizes mild electric currents to drive charged drug molecules across the skin, while sonophoresis employs ultrasound waves to increase skin permeability through mechanisms such as cavitation and thermal effects. Nanotechnology-based systems, including liposomes, solid lipid nanoparticles, nanoemulsions, polymeric nanoparticles, dendrimers, and nanocrystals, offer versatile platforms for enhanced drug solubility, stability, and targeted delivery.
How to cite this article:
Getu T. Emerging Technologies in Transdermal
Drug Delivery. Rec Trends Pharm Tech Ind 2024
6(1): 6-12.
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