Pharmacogenomics Advances: Customizing Drug Therapies for Individual Patients
Keywords:
Pharmacogenomics, Precision Medicine, Genetic Variations, Drug Metabolism, Personalized Medicine, Clinical Applications, Technological Advancements, Challenges, Ethical Considerations, Future ProspectAbstract
By adapting medication therapy to a patient’s genetic profile, the emerging science of pharmacogenomics, which combines genetics with pharmacology, promises to transform medical practice. The fundamental ideas of pharmacogenomics are clarified in this review paper, which also emphasizes how genetic variants affect how drugs work. Technological advancements in bioinformatics and high-throughput sequencing have enabled thorough genetic investigations, enabling the identification of critical variations connected to pharmacological effects. Clinical applications are found in many different medical specialties, such as oncology and psychiatry, where genetic knowledge improves treatment options and results. However, issues with diverse databases, variation interpretation, ethical issues need to be addressed. Looking ahead, the advancement of point-of-care genetic testing and the merging of pharmacogenomic data with other omics information both offer enormous potential. A \ comprehensive strategy to deal with these issues will be crucial in realizing pharmacogenomics’ revolutionary effects as it moves closer to being a standard part of medical care.
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