Analytical Review of Aschottana Procedure w.r.t. Ophthalmic Drug Delivery

Authors

  • Gavimath Shivanand PhD Scholar, Department of Post Graduate Studies in Shalakya Tantra, Parul Institute of Ayurveda, Parul University, Waghodia, Vadodara, Gujarat, India.
  • Rajeev G Dole Professor and HOD, Department of Post Graduate Studies in Shalakya Tantra, Parul Institute of Ayurveda, Parul University, Waghodia, Vadodara, Gujarat.

Abstract

Aschottana is one of the specialty procedure among kriyakalpas in which the herbal medications in the form of liquid are instilled into the conjunctival sac, drop by drop at a distance of 2 angulas is called as Aschottana. Ocular drugs are usually delivered locally to the eye. Required drug loading, release rate, and ocular retention time of drug delivery systems depend on the potency, bioavailability, and clearance of the drug at the target site. The concept of Aschottana is explained in different eye diseases with different combinations of herbs and minerals.This can be used in preventive and therapeutic conditions. Many herbal Aschottana preperations have also been introduced for ocular drug delivery. These novel formulations may help to surpass ocular barriers. Also, these novel devices and/or formulations possess high precorneal residence time, sustain the drug release, and enhance ocular bioavailability of therapeutics.

How to cite this article:
Shivanand G, Dole RG. Analytical Review of Aschottana Procedure w.r.t. Ophthalmic Drug Delivery. J Adv Res Ayur Yoga Unani Sidd Homeo. 2022;9(1&2): 1-4.

DOI: https://doi.org/10.24321/2394.6547.202201

References

Murty KRS. Sharngadhara Samhita a treatise on Ayurveda, Chaukamba Orientalia Varanasi; 2017.

Sharma PV. Dravyaguna Vignan-2013. Chaukhambha Sanskrith Prathistan. Sushruta, Sushruta Samhita, Ayurveda Tatva Sandeepika, Hindi Commentary, Chaukamba Samskruth Samsthana, Varanasi; 2012, Sutrasthana, 39/7.

Prakruthi G, Hamsaveni. Aschyotana, Aadya Upakrama in Sarva-Akshi Roga. WJPLS. 2017;3(4):216-25.

Tripathi SI. Gadanigraha of Sri Vaidya Sodhala. Pandeya G, editor. 3rd ed. Shloka 103. Chaukhambha Publications, Netragodhikara; 2011. 436 p.

Tripathi SI. Gadanigraha of Sri Vaidya Sodhala. Pandeya G, editor. 3rd ed. Shloka 135, 136. Chaukhambha Publications, Netragodhikara; 2011.

Tripathi SI. Gadanigraha of Sri Vaidya Sodhala. Pandeya G, editor. 3rd ed. Varanasi: Chaukhambha Orientalia; 2011. p. 104, 507.

Tripathi SI. Gadanigraha of Sri Vaidya Sodhala. Pandeya G, editor. 3rd ed. Shloka 138, 139. Chaukhambha Publications, Netragodhikara; 2011.

Teeka D. Sushrutha Samhita. Kavyathirtha NR, editor. Uttaratantra, Chapter 18, Ver 6. Varanasi: Chaukhambha Orientalia; 2009. p. 633, 824.

Indu. Ashtanga Sangraha of Vriddha Vagbhata. Shashilekha Sanskrit. Sharma S, editor. Sutra Sthana, Chapter 33. Ver 2. p. 694, 964

Teeka D. Sushrutha Samhita. Kavyathirtha NR, editor. Chapter 18. Verse 47. Varanasi: Chaukhambha Orientalia; 2009. p. 636, 824.

Teeka D. Sushrutha Samhita. Kavyathirtha NR, editor. Chapter 18. Verse 47. Varanasi: Chaukhambha Orientalia; 2009. p. 630, 824.

Ananthula HK, Vaishya RD, Barot M, Mitra AK. Duane’s Ophthalmology. In: Tasman W, Jaeger EA, editors. Bioavailability. Philadelphia: Lippincott Williams & Wilkins; 2009.

Patel A, Cholkar K, Agrahari V, Mitra AK. Ocular drug delivery systems: an overview. World J Pharmacol. 2013;2(2):47-64. [PubMed] [Google Scholar]

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Published

2022-06-01