Comparative Study of Efficacy and Safety of Coded Unani Formulations–UNIM-001+UNIM-003 with Methoxsalen in Cases of Bars (Vitiligo)

Abstract

Background: Vitiligo is a common acquired disorder of skin depigmentation in varying patterns, varying from small maculae’s with scalloping borders to near total depigmentation of body. The prevalence of vitiligo in India has been invariably reported between 0.25% and 4% of dermatology outpatients across studies from India and up to 8.8% in Gujarat and Rajasthan. The study was conducted to compare the coded Unani formulation UNIM-001 (tablet) and UNIM-003 (ointment) with Melanocyl tablet (10mg each) (Methoxsalen) as standard control.

Methodology: Sixty Five patients of trial group (UNIM-001+ UNIM-003) and sixty seven patients of control group (Comparator group) of 12-50 years of either sex were selected from patients attending the Out Patient Department (OPD), at RRIUM, Aligarh during 2015-18. The patients were treated for eight months with instructions and are followed every month for efficacy and safety of the drug(s). The CRF was maintained, and post treatmet followup was done at 3 months for the repigmentaion retained by the patient.

Result: The UNIM-001 (tablets) and UNIM -003 (ointment) and standard control drug Melanocyl tablets (methoxsalen) showed same results and did not show any side effects.

Conclusion: The trial drug and the standard control drugs both possess same anti- vitiligo efficacy and are also safe for the patients.

How to cite this article:
Khan P, Verma RS, Ayub S, Afza S, Akhtar J, Khan AA. Comparative Study of Efficacy and Safety of Coded Unani Formulations–UNIM-001+UNIM-003 with Methoxsalen in Cases of Bars (Vitiligo). J Adv Res Ayur Yoga Unani Sidd Homeo 2020; 7(3&4): 16-26.

DOI: https://doi.org/10.24321/2394.6547.202009