Comparative Clinical Study of ‘Panchavalkal Ointment’ & Framycetin Sulfate Cream (Local Application) in the Management of Infected Wound wrt Dushta Vrana

Authors

  • Anjna M Kulkarni Ph.D. (Scholar), Shalya Tantra, School of Ayurveda, D.Y. Patil University, Navi Mumbai, Maharashtra, India.
  • Amarprakash Dwivedi Professor, Shalya Tantra, School of Ayurveda, D.Y. Patil University, Navi Mumbai, Maharashtra, India. https://orcid.org/0000-0002-7986-0382

Keywords:

Infected Wound, Framycetin Sulfate, Dushta Vrana, Panchvalkal

Abstract

A wound infection is major cause of delayed wound healing. Although there is a huge range of wound care available from Western medicine, their own side effects and increased resistance towards micro-organism leave a substantial space for herbal productwhich can cope-up with the sign and symptom of wound infection as well as accelerate the wound healing. In this clinical study, Group A_Panchavalkal ointment was compared with Group B_Framycetin Sulfate cream, topically, in management of Dushta Vrana (infected wound). Assessment of pain was done by numerical rating scale. However, assessment of objective parameter such as size, depth, edges, undermining, necrotic tissue type, necrotic tissue amount, exudate type, exudate amount, skin color surrounding wound, peripheral tissue edema, peripheral tissue induration, granulation tissue, epithelialization evaluated by Bates-Jensen Wound Assessment Tool. The wound status continuum between the two groups after treatment was compared. In Group A, 30.0% woundachieved tissue health, 36.7% healed, 26.7 regenerated and 6.7% improved. In Group B only 13.3% woundachieved tissue health, 30.0% healed, 43.3% regenerated and 13.3% improved. The clinical analysis of objective parameters showed that both the medicines are effective to control wound infection, but it was observed that control in sign and symptom of wound infection was rapid in Group A and led to wound healing with less time duration in comparison to Group B. The wound assessment revealed that both the groups were markedly efficacious in treating infected wound ; moreover, the outcome was comparatively better in Group A. Hence, it is proved that Panchvalkal ointment was more effective than Framycetin Sulfate Cream in the management of infected wound w.s.r. to Dushta Vrana.  

How to cite this article: Kulkarni AM, Dwivedi A. Comparative Clinical Study of ‘Panchavalkal Ointment’ & Framycetin Sulfate Cream (Local Application) in the Management of Infected Wound wrt Dushta Vrana. J Adv Res Ayur Yoga Unani Sidd Homeo 2019; 6(3&4): 17-24.

DOI: https://doi.org/10.24321/2394.6547.201910

References

Love and Baily, Short Practice of Surgery. 25th edition. Norman S Williums, Edward Arnold (Publisher) Ltd. 2008; 24.

Bhat M Sriram. Manual of Surgery. 4th edition, Jaypee Brothers Medical Publishers (P) ltd. 2013; 5-7 & 14-18.

Bowler PG, Duerden I, Armstrong DG. Wound microbiology and associated approaches to wound management. clinical microbiology reviews 2001; 14(2): 244-269. Avaliable from: https://cmr.asm.org/ content/14/2/244.short [Google Scholar].

Wound infection & pain management. wound infection and pain management made easy. wounds international 2010; 1(3): Available from: http://www. woundsinternational.com.

Sushruta, Sushruta Samhita, Part-I, Ayurveda Tatwa Sandeepika Hindi Commentary, Edited by Kaviraj Ambika Dutta Shastri, Sutrastana-Vrana prashna aadhyaya 21/ 40, Chaukhamba Sanskrit Sansthan, Varanasi, Edition 13, 2002; 94.

Sushruta, Sushruta Samhita, Part-I, Ayurveda Tatwa Sandeepika Hindi Commentary, Edited by Kaviraj Ambika Dutta Shastri, Chikitsasthana - Dvivraneeya Chikitsa 1/8, Chaukhamba Sanskrit Sansthan, Varanasi, Edition-13, 2002; 4,8,19.

Sakhitha KS, Dattatray D, Santhosh B, Suresh P. Formulation, anti-bacterial activity and wound healing property of panchavalkaladi ointment. International ayurvedic medical journal 2013; 1(4): 1-5. Available from: http://www.iamj.in/posts/images/upload/iamj4.1.pdf.

Bhat KS, Vishwesh BN, Sahu M, Shukla VK. A clinical study on the efficacy of panchavalkala cream in vrana shodhana w.s.r to its action on microbial load and wound infection. Ayu 2014; 35(2): 135-140. [ResearchGate/ PubMed/ Google Scholar].

Salem MZM, Salem AZM, Camacho LM, Ali HM. Antimicrobial activities and phytochemical composition of extracts of ficus species: an over view. African Journal of Microbiology Research 2013; 7(33): 4207-4219. Avaliable from: https://academicjournals.org/article/ article1380273000_Salem%20et%20al.pdf [Google Scholar].

Bates-Jensen BM, McNees P. Toward an intelligent wound assessment system. Ostomy Wound Manage 1995; 41(suppl 7a): 80s-85s. [PubMed/ Google Scholar].

Shri Bhavamishra, Bhavprakasha, Poorva Khanda. Mishraprakaranam, 6/202. In: Mishra SB, Vaishya SR, editors. 8th ed. I. Varanasi: Chaukhambha Sanskrit Bhawan; 2012; 189.

Asolkar LV, Kakar KK, Chakraborty OJ. New Delhi: Publications and Information Directorate, Council of Scientific and Industrial Research; 1965. A Glossary of Indian Medicinal Plants with Active Principal. Part-I; 81.

Vagbhata, Ashtanga Hridaya, Sutrasthana . Rasabhedeeya Adhyaya, 10/21. In: Vaidya BH, editor. 9th ed. Varanasi: Chaukhamba Orientalia Publication; 2002; 176.

Patil VV, Pimpikar VR. Pharmacognostical studies and evaluation of anti-inflammatory activity of Ficus bengalensis linn. J Young Pharm 2009; 1(1): 110-111. Avaliable from: http://www.jyoungpharm.in/article. asp?issn=0975-1483;year=2009;volume=1;issue=1; spage=49;epage=53;aulast=Patil [PubMed/ Goolge Scholar].

Preeti R, Devanathan VV, Loganathan M. Antimicrobial and antioxidant efficacy of some medicinal plants against food borne pathogens. Adv Biol Res 2010; 4: 122-125. [ResearchGate].

Downloads

Published

2020-03-07