http://medicaljournalshouse.com/index.php/JDrug-Discovery-Development Journal of Drug Discovery and Development Advanced Research Publications en-US Journal of Drug Discovery and Development ( ISSN:2581-6861) 2581-6861 <p>We, the undersigned, give an undertaking to the following effect with regard to our article entitled<br>“_______________________________________________________________________________________________________________________________________________________________________________<br>________________________________________________________________________________” submitted for publication in (Journal title)________________________________________________ _______________________________________________________Vol.________, Year _________:-</p> <p>1. The article mentioned above has not been published or submitted to or accepted for publication in any form, in any other journal.</p> <p>2. We also vouchsafe that the authorship of this article will not be contested by anyone whose name(s) is/are not listed by us here.</p> <p>3. I/We declare that I/We contributed significantly towards the research study i.e., (a) conception, design and/or analysis and interpretation of data and to (b) drafting the article or revising it critically for important intellectual content and on (c) final approval of the version to be published.</p> <p>4. I/We hereby acknowledge ADRs conflict of interest policy requirement to scrupulously avoid direct and indirect conflicts of interest and, accordingly, hereby agree to promptly inform the editor or editor's designee of any business, commercial, or other proprietary support, relationships, or interests that I/We may have which relate directly or indirectly to the subject of the work.</p> <p>5. I/We also agree to the authorship of the article in the following sequence:-</p> <p>Authors' Names (in sequence) Signature of Authors<br>1. _____________________________________ _____________________________________<br>2. _____________________________________ _____________________________________<br>3. _____________________________________ _____________________________________<br>4. _____________________________________ _____________________________________<br>5. _____________________________________ _____________________________________<br>6. _____________________________________ _____________________________________<br>7. _____________________________________ _____________________________________<br>8. _____________________________________ _____________________________________</p> <p>Important</p> <p>(I). All the authors are required to sign independently in this form in the sequence given above. In case an author has left the institution/ country and whose whereabouts are not known, the senior author may sign on his/ her behalf taking the responsibility.</p> <p>(ii). No addition/ deletion/ or any change in the sequence of the authorship will be permissible at a later stage, without valid reasons and permission of the Editor.</p> <p>(iii). If the authorship is contested at any stage, the article will be either returned or will not be<br>processed for publication till the issue is solved.</p> http://medicaljournalshouse.com/index.php/JDrug-Discovery-Development/article/view/1081 <p>Biofilms, complex microbial communities embedded in extracellular polymeric substances, pose significant challenges in pharmaceutical environments. This review explores the formation, characteristics, and impact of biofilms in pharmaceutical manufacturing settings. It discusses the challenges associated with biofilm formation, the risks to product quality, and strategies employed for effective control. Understanding and addressing biofilm-related issues are crucial for maintaining the sterility and safety of pharmaceutical products.</p> <p>How to cite this article:</p> <p>Mishra A, Singh P. Biofilms in Pharmaceutical<br />Environments: Challenges and Strategies for<br />Control. J Durg Dis Dev 2023; 7(2): 1-6.</p> Akansha Mishra Pragati Singh Copyright (c) 2023 Author's https://www.advancedresearchpublications.com/image/catalog/OPEN%20ACCESS%20LICENCE%20TO%20PUBLISH%20(JoCD).pdf 2023-12-30 2023-12-30 7 2 http://medicaljournalshouse.com/index.php/JDrug-Discovery-Development/article/view/1082 <p>Antibody-based therapeutics have witnessed remarkable advancements in recent years, transforming the landscape of medical treatment. This comprehensive review explores the current trends in antibody-based therapeutics, with a focus on monoclonal antibodies (mAbs), immune checkpoint inhibitors, antibody-drug conjugates (ADCs), bispecific antibodies, and nanobody technology.</p> <p>How to cite this article:<br />Deshmukh P, Singh K, Singh V. Current Trends<br />in Antibody-Based Therapeutics. J Durg Dis Dev<br />2023; 7(2): 7-11.</p> Vidhi Singh Kanchan Singh Prabhas Deshmukh Copyright (c) 2023 Author's https://www.advancedresearchpublications.com/image/catalog/OPEN%20ACCESS%20LICENCE%20TO%20PUBLISH%20(JoCD).pdf 2023-12-30 2023-12-30 7 2 7 11 http://medicaljournalshouse.com/index.php/JDrug-Discovery-Development/article/view/1083 <p>Fungal contamination poses a significant threat to pharmaceutical products, potentially compromising their safety and efficacy. In this review the aspects of fungal contamination in pharmaceuticals, focusing on the identification methods and control strategies employed to mitigate this risk. Understanding the sources, detection techniques, and preventive measures is crucial for maintaining the integrity of pharmaceutical products and ensuring patient safety.</p> <p>How to cite this article:</p> <p>Ranawat D, Singhal P, Kumar A. Fungal<br />Contamination in Pharmaceuticals Identification<br />and Control Strategies. J Durg Dis Dev 2023;<br />7(2): 12-20.</p> Dristi Ranawat Pooja Singhal Aditi Kumar Copyright (c) 2023 Author's https://www.advancedresearchpublications.com/image/catalog/OPEN%20ACCESS%20LICENCE%20TO%20PUBLISH%20(JoCD).pdf 2023-12-30 2023-12-30 7 2 12 20 http://medicaljournalshouse.com/index.php/JDrug-Discovery-Development/article/view/1087 <p>Microorganisms play a pivotal role in various stages of drug development, contributing to the discovery, production, and testing of pharmaceuticals. It provides an extensive examination of the multifaceted interactions between microorganisms and drug development processes. From natural product discovery to fermentation-based production and microbiome research, microorganisms influence drug development significantly. Understanding these microbial contributions is crucial for advancing drug development strategies and fostering innovation<br />in the pharmaceutical industry.</p> <p>How to cite this article:</p> <p>Kshitij K, Tyagi A, khuswah A. Role of<br />Microorganisms in Drug Development: A<br />Comprehensive Review. J Durg Dis Dev 2023;<br />7(2): 27-31.</p> karan kshitij Arushi Tyagi Aarti khuswah Copyright (c) 2023 Author's https://www.advancedresearchpublications.com/image/catalog/OPEN%20ACCESS%20LICENCE%20TO%20PUBLISH%20(JoCD).pdf 2023-12-30 2023-12-30 7 2 27 31 http://medicaljournalshouse.com/index.php/JDrug-Discovery-Development/article/view/1084 <p>Protein folding is a highly orchestrated process crucial for maintaining cellular homeostasis. However, aberrant protein folding can lead to misfolding, resulting in the accumulation of misfolded proteins and contributing to the pathogenesis of various diseases. This review explores the intricate mechanisms of protein folding, the consequences of misfolding, and the therapeutic strategies aimed at addressing protein misfolding disorders.</p> <p>How to cite this article:<br />Jain A, Tyagi P. Protein Folding and Misfolding<br />Implications for Disease and Therapeutics. J Durg<br />Dis Dev 2023; 7(2): 21-26.</p> Akshita Jain Pallavi Tyagi Copyright (c) 2023 Author's https://www.advancedresearchpublications.com/image/catalog/OPEN%20ACCESS%20LICENCE%20TO%20PUBLISH%20(JoCD).pdf 2023-12-31 2023-12-31 7 2 21 26