Journal of Drug Discovery and Development ( ISSN:2581-6861)

Biofilms in Pharmaceutical Environments: Challenges and Strategies for Control

2024-02-07T06:37:36+00:00

Biofilms, complex microbial communities embedded in extracellular polymeric substances, pose significant challenges in pharmaceutical environments. This review explores the formation, characteristics, and impact of biofilms in pharmaceutical manufacturing settings. It discusses the challenges associated with biofilm formation, the risks to product quality, and strategies employed for effective control. Understanding and addressing biofilm-related issues are crucial for maintaining the sterility and safety of pharmaceutical products.

How to cite this article:

Mishra A, Singh P. Biofilms in Pharmaceutical
Environments: Challenges and Strategies for
Control. J Durg Dis Dev 2023; 7(2): 1-6.

Current Trends in Antibody-Based Therapeutics

2024-02-07T06:41:07+00:00

Antibody-based therapeutics have witnessed remarkable advancements in recent years, transforming the landscape of medical treatment. This comprehensive review explores the current trends in antibody-based therapeutics, with a focus on monoclonal antibodies (mAbs), immune checkpoint inhibitors, antibody-drug conjugates (ADCs), bispecific antibodies, and nanobody technology.

How to cite this article:
Deshmukh P, Singh K, Singh V. Current Trends
in Antibody-Based Therapeutics. J Durg Dis Dev
2023; 7(2): 7-11.

Fungal Contamination in Pharmaceuticals Identification and Control Strategies

2024-02-07T06:46:50+00:00

Fungal contamination poses a significant threat to pharmaceutical products, potentially compromising their safety and efficacy. In this review the aspects of fungal contamination in pharmaceuticals, focusing on the identification methods and control strategies employed to mitigate this risk. Understanding the sources, detection techniques, and preventive measures is crucial for maintaining the integrity of pharmaceutical products and ensuring patient safety.

How to cite this article:

Ranawat D, Singhal P, Kumar A. Fungal
Contamination in Pharmaceuticals Identification
and Control Strategies. J Durg Dis Dev 2023;
7(2): 12-20.

Role of Microorganisms in Drug Development: A Comprehensive Review

2024-02-07T07:30:10+00:00

Microorganisms play a pivotal role in various stages of drug development, contributing to the discovery, production, and testing of pharmaceuticals. It provides an extensive examination of the multifaceted interactions between microorganisms and drug development processes. From natural product discovery to fermentation-based production and microbiome research, microorganisms influence drug development significantly. Understanding these microbial contributions is crucial for advancing drug development strategies and fostering innovation
in the pharmaceutical industry.

How to cite this article:

Kshitij K, Tyagi A, khuswah A. Role of
Microorganisms in Drug Development: A
Comprehensive Review. J Durg Dis Dev 2023;
7(2): 27-31.

Protein Folding and Misfolding Implications for Disease and Therapeutics

2024-02-07T07:06:43+00:00

Protein folding is a highly orchestrated process crucial for maintaining cellular homeostasis. However, aberrant protein folding can lead to misfolding, resulting in the accumulation of misfolded proteins and contributing to the pathogenesis of various diseases. This review explores the intricate mechanisms of protein folding, the consequences of misfolding, and the therapeutic strategies aimed at addressing protein misfolding disorders.

How to cite this article:
Jain A, Tyagi P. Protein Folding and Misfolding
Implications for Disease and Therapeutics. J Durg
Dis Dev 2023; 7(2): 21-26.