Psoriasis: A General Review.
Keywords:
Psoriasis, National Psoriasis Foundation, Monozygotic twins, Dizygotic twins and Genetic.Abstract
Psoriasis occurs equally in both sexes, and it can occur and affect anyone at any age, but mostly it appears for the first time in young people between the ages of 15 and 25 years. Its prevalence in Western populations is estimated to be approximately 2–3%. Graphical plots
showed an increasing prevalence of psoriasis with each consecutive survey in all examined age groups and birth cohorts, leaving time period effects as the explanation for the increase. The study found that 35% of people with psoriasis could be classified as having moderate
to severe psoriasis.
We found a family history of the disease in around one-third of people with psoriasis, and researchers have also identified the presence of genetic loci associated with it. There is a 70% chance of a twin developing psoriasis if the other twin has psoriasis in monozygotic twins. But concordance is around 20% for dizygotic twins. Thus, we find both a genetic predisposition and an environmental response in the development of psoriasis.
We found a family history of the disease in around one-third of people with psoriasis, and researchers have also identified the presence of genetic loci associated with it. There is a 70% chance of a twin developing psoriasis if the other twin has psoriasis in monozygotic twins. But concordance is around 20% for dizygotic twins. Thus, we find both a genetic predisposition and an environmental response in the development of psoriasis.
References
A P I text book of Medicine, edited by Dr Siddharth Shah, 7th edition Mumbai, National book Depot, 2003.
Harshmohan, Text book of Pathology – 4th ed. Reprint 2002, New Delhi: Jay Pee brothers Medical Publishers (P) Ltd, 2002.
K. Sembulingam & Prema Sembulingam, Essentials of Medical Physiology, New Delhi, Jaypee Brothers, 2nd edition, reprint 2003.
Ramji Gupta- Text Book of Dermatology , 1st edition, New Delhi: Jay Pee brothers Medical Publishers 2002.
Virendra N Sehagal. Text book of Clinical Dermatology,4th edition, New Delhi: Jay Pee brothers Medicdal Publishers (P) Ltd, 2006.
Rook Wilkinson Ebligs Rook. Textbook of Dermatology, 6th ed. Vol.2, Mc Graw Hill Publications, USA 1999.
http:// www.who.int./psoriasis.com
.Guyton and Hall,Textbook of Medical Physiology,12thedition,Philadelphia An imprint of Elsevier ;2011..
Gupta GK,Devi G,.Modern Physiology,Vol First,First edition ,Merut: Utkarsha prakashan ;2012.P 47-50.
C C Chattergee.Human Physiology,Vol.1.11th edition,CBS Publisher and distributor pvt ltd .
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