Morphological Analysis of Body Fluids for Diagnostic Significance
Keywords:
Pleural fluid, Ascitic Fluid, Cerebrospinal FluidAbstract
Introduction: Effusion cytology is the first line of investigation in a suspected case of infections and malignancy. Aetiological diagnosis of effusion samples is challenging and morphological analysis provides valuable information in the evaluation of body fluids. It also helps in studying the infections and staging of malignancies and assessing the prognosis of the disease.
Objective: To know the diagnostic significance of morphological analysis in body fluids.
Methods: The retrospective study was carried out on 500 cases.
Results: The majority (52%) of cases were due to tuberculosis. Other diseases causing different effusions were: (13%) congestive heart failure cases, bacterial infection cases (26%), viral infection cases (8%), cirrhosis of liver cases, (3%) pneumonia cases(3%), renal failure cases (2%), and chronic obstructive pulmonary disease (2%) cases.
How to cite this article:
Kaur N, Sharma A, Singh M, Ranga S, Mung C. Morphological Analysis of Body Fluids for Diagnostic. Rec Adv Path Lab Med. 2022;8(1&2):7-9.
DOI: https://doi.org/10.24321/2454.8642.202211
References
Srinivasan R, Rekhi B, Rajwanshi A, Pathuthara S, Mathur S, Jain D, Gupta N, Gautam U, Rai N, Nijhawan VS, Iyer V. Indian academy of cytologists guidelines for collection, preparation, interpretation, and reporting of serous effusion fluid samples. J Cytol. 2020;37(1):1. [PubMed] [Google Scholar]
Nathan NA, Narayan E, Smith MM, Horn MJ. Cell Block Cytology. Improved preparation and its efficacy in diagnostic cytology. Am J ClinPathol. 2000 Oct 1;114(4):599-606. [PubMed] [Google Scholar]
Fetsch PA, Simsir A, Brosky K, Abati A. Comparison of three commonly used cytologic preparations in effusion immuno cyto chemistry. Diagn Cytopathol. 2002 Jan;26(1):61-6. [PubMed] [Google Scholar]
Krogerus L, Kholová I. Cell Block in Cytological Diagnostics: Review of Preparatory Techniques. Acta Cytol. 2018;62(4):237-43. [PubMed] [Google Scholar]
Sudha KG, Houser PM, Shotsberger-Gray W, Chajewski OS, Yang J. Young Investigator Challenge: A novel, simple method for fluid preparation, implementation, and use over 2 years. Cancer Cytopathol. 2016 Dec;124(12):885- 92. [PubMed] [Google Scholar]
Tynski Z, Wasman J, Abdul-Karim F, Wang N. Comparison of cell block preparation methods for non-gynecologic Thin Prep specimens. Diagn Cytopathol. 2007 Oct;35(10):640-3. [PubMed] [Google Scholar]
Kulkarni R. Cytologic analysis of body fluids with an emphasis on malignant effusions. Indian J Pathol Oncol. 2020 Dec 28;5(1):106-11. [PubMed] [Google Scholar]
Lekha NB, Choudhary S, Manjunatha YA. Cytomorphological analysis of body fluids in tertiary care centre. Indian J Pathol Oncol. 2020 Aug 28;7(3):498- 501. [Google Scholar]
Frist B, Kahan AV, Koss LG. Comparison of the Diagnostic Values of Biopsies of the Pleura and Cytologic Evaluation of Pleural Fluids. Am J Clin Pathol. 1979 Jul 1;72(1):48- 51. [PubMed] [Google Scholar]
Murphy WM, Ng ABP. Determination of Primary Site by Examination of Cancer Cells in Body Fluids. Am J Clin Pathol. 1972 Nov 1;58(5):479-88. [Google Scholar]
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