Paediatric Nasal Rhinosporidiosis – An Overlooked Clinical Diagnosis in Non-Endemic Region
Keywords:
Rhinosporidiosis, Nasal, Granulomatosis, PaediatricAbstract
Nasal obstruction is an important clinical complaint in the adolescent age group and may lead to several early and late sinonasal complications. Rhinosporidiosis, an endemic disease of the Southern part of India, is an important differential diagnosis of nasal obstruction. Its causal organism is Rhinosporidium seeberi fungus. The condition involves the mucosa of the nose, nasal septum, middle nasal turbinate, and floor. Surgical excision of the lesion is the preferred treatment. The authors have described a case of paediatric nasal rhinosporidiosis in Northern India where the incidence is relatively low, and hence there are more chances of missing the diagnosis on clinical examination.
References
Leboulanger N. Nasal obstruction in children. Eur Ann Otorhinolaryngol Head Neck Dis. 2016 Jun;133(3):183- 6. [PubMed] [Google Scholar]
Nwawka OK, Nadgir R, Fujita A, Sakai O. Granulomatous disease in the head and neck: developing a differential diagnosis. Radiographics. 2014;34(5):1240-56. [PubMed] [Google Scholar]
Almeida FA, Feitoza LM, Pinho JD, Mello GC, Lages JS, Silva FF, Silva RR, Silva GE. Rhinosporidiosis: the largest case series in Brazil. Rev Soc Bras Med Trop [Internet]. 2016 [cited 2023 Sep 15];49(4):473-6. Available from: https://pubmed.ncbi.nlm.nih.gov/27598634/
[PubMed] [Google Scholar]
Izimukwiye AI, Mbarushimana D, Ndayisaba MC, Bigirimana V, Rugwizangoga B, Laga AC. Cluster o nasal rhinosporidiosis, Eastern Province, Rwanda. Emerg Infect Dis. 2019 Sep;25(9):1727-9. [PubMed] [Google Scholar]
Ahluwalia KB. Causative agent of rhinosporidiosis. J Clin Microbiol. 2001 Jan;39(1):413-5. [Google Scholar]
Mendoza L, Taylor JW, Ajello L. The class Mesomycetozoea: a heterogeneous group of microorganisms at the animal-fungal boundary. Annu Rev Microbiol. 2002;56:315-44. [PubMed] [Google Scholar]
Das S, Kashyap B, Barua M, Gupta N, Saha R, Vaid L, Banka A. Nasal rhinosporidiosis in humans: new interpretations and a review of the literature of this enigmatic disease. Med Mycol [Internet]. 2011 Apr [cited 2019 Oct 21];49(3):311-5. Available from: https:// academic.oup.com/mmy/article/49/3/311/1095671/ [PubMed] [Google Scholar]
Branscomb R. Rhinosporidiosis update. Lab Med. 2002 Aug 1;33(8):631-3. [Google Scholar]
Vélez A, Jiménez G, Hidrón A, Talero S, Agudelo CA. Rhinosporidiosis in Colombia: case series and literature review. Trop Doct. 2018;48(4):289-93. [PubMed] [Google Scholar]
Devaraja K, Sagar P, Singh CA, Kumar R. Nondisseminated rhinosporidiosis with multisite involvement in the head and neck. Ear Nose Throat J [Internet]. 2018 [cited 2023 Sep 15];97(9):E15-7. Available from: https:// pubmed.ncbi.nlm.nih.gov/30273436/ [PubMed] [Google Scholar]
Arseculeratne SN, Atapattu DN, Wickramaratne K. Nature and significance of the electron-dense bodies of the endospores of rhinosporidium seeberi: their reactions with MTT (3-[4,5-dimethyl-2-thiazolyl]- 2,5-diphenyl-2H-tetrazolium bromide) and TMRE (tetramethyl-rhodamine ethyl ester). Med Mycol [Internet]. 2005 May [cited 2023 Sep 15];43(3):261- 73. Available from: https://pubmed.ncbi.nlm.nih. gov/16010853/ [PubMed] [Google Scholar]
Bakshi SS. Rhinosporidiosis. J Allergy Clin Immunol Pract [Internet]. 2017 [cited 2023 Sep 15];5(6):1739. Available from: https://pubmed.ncbi.nlm.nih.gov/28757369/ [PubMed] [Google Scholar]
Chen L, Buonocore D, Wang B, Tabaee A. Delayed recurrence of sinonasal rhinosporidiosis. Am J Otolaryngol [Internet]. 2015 [cited 2023 Sep 15];36(6):778-80. Available from: https://pubmed. ncbi.nlm.nih.gov/26545470 [PubMed] [Google Scholar ]
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