Flaxseeds and their Role in Polycystic Ovary Syndrome Treatment
Keywords:
Polycystic Ovary Syndrome, Oligomenorrhea, Hyperandrogenemia, polycystic ovaries, Herbal medicine, Complementary therapies, FlaxseedReferences
Gu, Y., Zhou, G., Zhou, F., Wu, Q., Ma, C., Zhang, Y., Ding, J., & Hua, K. (2022). Life Modifications and PCOS: Old Story But New Tales. Frontiers in endocrinology, 13, 808898. https://doi.org/10.3389/fendo.2022.808898
Mills, G., Badeghiesh, A., Suarthana, E., Baghlaf, H., & Dahan, M. H. (2020). Associations between polycystic ovary syndrome and adverse obstetric and neonatal outcomes: a population study of 9.1 million births. Human reproduction (Oxford, England), 35(8), 1914–1921. https://doi.org/10.1093/humrep/deaa144
Hardiman, P., Pillay, O. C., & Atiomo, W. (2003). Polycystic ovary syndrome and endometrial carcinoma. Lancet (London, England), 361(9371), 1810–1812. https://doi.org/10.1016/s0140-6736(03)13409-5
Escobar-Morreale H. F. (2018). Polycystic ovary syndrome: definition, aetiology, diagnosis and treatment. Nature reviews. Endocrinology, 14(5), 270–284. https://doi.org/10.1038/nrendo.2018.24
Hart R. (2008). PCOS and infertility. Panminerva medica, 50(4), 305–314.
Dokras, A., Saini, S., Gibson-Helm, M., Schulkin, J., Cooney, L., & Teede, H. (2017). Gaps in knowledge among physicians regarding diagnostic criteria and management of polycystic ovary syndrome. Fertility and sterility, 107(6), 1380–1386.e1. https://doi.org/10.1016/j.fertnstert.2017.04.011
Islam, H., Masud, J., Islam, Y. N., & Haque, F. K. M. (2022). An update on polycystic ovary syndrome: A review of the current state of knowledge in diagnosis, genetic etiology, and emerging treatment options. Women's health (London, England), 18, 17455057221117966. https://doi.org/10.1177/17455057221117966
Rashid, R., Mir, S. A., Kareem, O., Ali, T., Ara, R., Malik, A., Amin, F., & Bader, G. N. (2022). Polycystic ovarian syndrome-current pharmacotherapy and clinical implications. Taiwanese journal of obstetrics & gynecology, 61(1), 40–50. https://doi.org/10.1016/j.tjog.2021.11.009
Speelman D. L. (2019). Nonpharmacologic Management of Symptoms in Females With Polycystic Ovary Syndrome: A Narrative Review. The Journal of the American Osteopathic Association, 119(1), 25–39. https://doi.org/10.7556/jaoa.2019.006
Nowak, D. A., Snyder, D. C., Brown, A. J., & Demark-Wahnefried, W. (2007). The Effect of Flaxseed Supplementation on Hormonal Levels Associated with Polycystic Ovarian Syndrome: A Case Study. Current topics in nutraceutical research, 5(4), 177–181.
Gambineri, A., Pelusi, C., Vicennati, V., Pagotto, U., & Pasquali, R. (2002). Obesity and the polycystic ovary syndrome. International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity, 26(7), 883–896. https://doi.org/10.1038/sj.ijo.0801994
Marshall K. (2001). Polycystic ovary syndrome: clinical considerations. Alternative medicine review : a journal of clinical therapeutic, 6(3), 272–292.
King J. (2006). Polycystic ovary syndrome. Journal of midwifery & women's health, 51(6), 415–422. https://doi.org/10.1016/j.jmwh.2006.01.008
Thompson, LU. Flaxseed, lignans, and cancer. In: Cunnane, SC.; Thompson, LU., editors. Flaxseed in human nutrition. Chicago, IL: AOCS Press; 1995. p. 219-236.
Al-Nawass KJ, 2015. Effect of different levels of golden flaxseed (Linum usitatissimum L.) powder on some blood biochemical quality of male and female broiler. Res. Opin. Anim. Vet. Sci., 5(11): 425-428
Goyal, A., Sharma, V., Upadhyay, N., Gill, S., & Sihag, M. (2014). Flax and flaxseed oil: an ancient medicine & modern functional food. Journal of food science and technology, 51(9), 1633–1653. https://doi.org/10.1007/s13197-013-1247-9
Singh, K. K., Mridula, D., Rehal, J., & Barnwal, P. (2011). Flaxseed: a potential source of food, feed and fiber. Critical reviews in food science and nutrition, 51(3), 210–222. https://doi.org/10.1080/10408390903537241+
Soni R P, Katoch M,Kumar A, Verma P, Flaxseed:composition and its health benefits.Res Environ Life Sci.2016;9:310-16.
Austria, J. A., Richard, M. N., Chahine, M. N., Edel, A. L., Malcolmson, L. J., Dupasquier, C. M., & Pierce, G. N. (2008). Bioavailability of alpha-linolenic acid in subjects after ingestion of three different forms of flaxseed. Journal of the American College of Nutrition, 27(2), 214–221
Haidari, F., Banaei-Jahromi, N., Zakerkish, M., & Ahmadi, K. (2020). The effects of flaxseed supplementation on metabolic status in women with polycystic ovary syndrome: a randomized open-labeled controlled clinical trial. Nutrition journal, 19(1), 8. https://doi.org/10.1186/s12937-020-0524-
Toulabi, T., Yarahmadi, M., Goudarzi, F., Ebrahimzadeh, F., Momenizadeh, A., & Yarahmadi, S. (2022). Effects of flaxseed on blood pressure, body mass index, and total cholesterol in hypertensive patients: A randomized clinical trial. Explore (New York, N.Y.), 18(4), 438–445. https://doi.org/10.1016/j.explore.2021.05.003
Rodriguez-Leyva, D., Weighell, W., Edel, A. L., LaVallee, R., Dibrov, E., Pinneker, R., Maddaford, T. G., Ramjiawan, B., Aliani, M., Guzman, R., & Pierce, G. N. (2013). Potent antihypertensive action of dietary flaxseed in hypertensive patients. Hypertension (Dallas, Tex. : 1979), 62(6), 1081–1089. https://doi.org/10.1161/HYPERTENSIONAHA.113.02094
Torkan, M., Entezari, M. H., & Siavash, M. (2015). Effect of flaxseed on blood lipid level in hyperlipidemic patients. Reviews on recent clinical trials, 10(1), 61–67. https://doi.org/10.2174/1574887110666150121154334
Almehmadi, A., Lightowler, H., Chohan, M., & Clegg, M. E. (2021). The effect of a split portion of flaxseed on 24-h blood glucose response. European journal of nutrition, 60(3), 1363–1373. https://doi.org/10.1007/s00394-020-02333-x
Sun, J., Bai, H., Ma, J., Zhang, R., Xie, H., Zhang, Y., Guo, M., & Yao, J. (2020). Effects of flaxseed supplementation on functional constipation and quality of life in a Chinese population: A randomized trial. Asia Pacific journal of clinical nutrition, 29(1), 61–67. https://doi.org/10.6133/apjcn.202003_29(1).0009
Ibrügger, S., Kristensen, M., Mikkelsen, M. S., & Astrup, A. (2012). Flaxseed dietary fiber supplements for suppression of appetite and food intake. Appetite, 58(2), 490–495. https://doi.org/10.1016/j.appet.2011.12.024
Haidari, F., Banaei-Jahromi, N., Zakerkish, M., & Ahmadi, K. (2020). The effects of flaxseed supplementation on metabolic status in women with polycystic ovary syndrome: a randomized open-labeled controlled clinical trial. Nutrition journal, 19(1), 8. https://doi.org/10.1186/s12937-020-0524-5
Fatima Farzana K1, Abubacker Sulaiman F2, Ruckmani A*1, Vijayalakshmi K3, Karunya Lakshmi G2, Shri Ranjini S2, Duraivel M1. Effects of Flax Seeds Supplementation in PolyCystic Ovarian Syndrome Int. J. Pharm. Sci. Rev. Res. 2015; 31:113-119
Mirmasoumi, G., Fazilati, M., Foroozanfard, F., Vahedpoor, Z., Mahmoodi, S., Taghizadeh, M., Esfeh, N. K., Mohseni, M., Karbassizadeh, H., & Asemi, Z. (2018). The Effects of Flaxseed Oil Omega-3 Fatty Acids Supplementation on Metabolic Status of Patients with Polycystic Ovary Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial. Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 126(4), 222–228. https://doi.org/10.1055/s-0043-119751
Lakshmi, J. N., Babu, A. N., Kiran, S. S. M., Nori, L. P., Hassan, N., Ashames, A., Bhandare, R. R., & Shaik, A. B. (2023). Herbs as a Source for the Treatment of Polycystic Ovarian Syndrome: A Systematic Review. Biotech (Basel (Switzerland)), 12(1), 4. https://doi.org/10.3390/biotech12010004